Categories: Disease A-Z

What is What is ulcerative colitis? ? – A-Z Disease

Definition

What is Ulcerative Colitis?

Ulcerative Colitis (UC) or ulcerative colitis is a disease that causes inflammation of the walls of the digestive tract. This disease is one of the conditions of inflammation of the large intestine or inflammatory bowel disease (IBD).

The presence of irritation or inflammation in the intestinal wall can interfere with the process of digesting and absorbing nutritional food into the body. Inflammation that occurs can sometimes cause bleeding to cause pus and mucus.

There are several types of ulcerative colitis:

  1. Ulcerative proctitis: Ulcerative proctitis is an inflammatory condition located in the rectum. This inflammation is likely to cause anal bleeding. Ulcerative proctitis is the most common type of ulcerative colitis, mild and has few complications.
  2. Proctosigmoiditis: Ulcerative colitis is a type of inflammation in the rectum and sigmoid colon (lower end of the colon). You will generally experience, inability to defecate, though there is encouragement to do it do it (heartburn), here called tenesmus.
  3. Left-sided colitis: This inflammation is also known as limited or distal colitis. Where this colitis occurs on the left side of the large intestine (rectum, sigmoid colon, and descending colon).
  4. Pancolitis: Pancolitis is when there is inflammation of ulcerative colitis in all parts of the intestine.

How common Ulcerative Colitis occur?

Men and women have the same possibility to experience Ulcerative Colitis and usually ulcerative colitis is a hereditary disease. People aged 15-35 years are the most affected by this disease. Most people suffer from UC for the rest of their lives. About half of the sufferers Ulcerative Colitis have mild symptoms but others have more severe and frequent symptoms.

Signs & Symptoms

What are the characteristics and symptoms of ulcerative colitis ?

Ulcerative colitis symptoms generally disappear and arise. When active symptoms appear, this is called flare-ups. Flare-ups the condition can be classified as severe, and occurs for several days or weeks and then goes into remission. Remission is a condition where there is little inflammation of the large intestine.

Ulcerative colitis is a condition that can cause your large intestine to swell and can cause small perforations. Perforation allows feces to leak into your stomach, which can cause life-threatening infections (peritonitis).

The symptoms ulcerative colitis or ulcerative colitis are:

  • stomach ache and diarrhea
  • slimy, bleeding stools
  • fatigue
  • weight loss
  • anorexia
  • fever

Other symptoms can also be affected by inflammation in the large intestine, including joint pain in the knee, ankle and wrist. Symptoms of ulcerative colitis can also affect the eyes.

If you suffer from ulcerative colitis for a long time, you may experience symptoms in other areas of your body such as rashes, thrush, and joint pain.

When people with ulcerative colitis have a bowel movement, the possibility of pain in the left side of the abdomen will subside slightly. In addition, there are still some characteristics and symptoms not mentioned above. If you have the same complaint, please consult your doctor.

When should I call the doctor?

You should contact a doctor if you find any of the symptoms below:

  • Fever or fever
  • Increased frequency of bowel movements, or bleeding
  • Flatulence, abdominal pain, or start vomiting.

Cause

Whatever causes it Ulcerative Colitis ?

The exact cause of this disease is still uncertain. Previously, most doctors thought that a strict diet and stress were the causes of ulcerative colitis.

But lately doctors have seen that these factors are not the main cause, but only conditions that can worsen ulcerative colitis.

Another suspected cause ulcerative colitis is immune dysfunction. When the immune system is supposed to fight viruses and bacteria, the abnormal immune system attacks cells of the digestive system itself.

Genetic factors also play an important role in causing ulcerative colitis, because this disease is more often found in families who have members with a tendency to be affected by this condition.

Even so, many patients who do not have a family health history who experience ulcerative colitis.

Risk factors

Anything that increases your risk of contracting Ulcerative Colitis ?

Some of the risk factors below can affect your likelihood of being affected ulcerative colitis is:

  • Age. The condition of ulcerative colitis usually appears before the age of 30. Even so, the condition can also occur at any age, and there are even some people who have just had the disease at the age of 60.
  • Race. This condition can occur in any racial group. However, white people have a higher risk of infection than Asians.
  • Family history. You are at higher risk of developing ulcerative colitis if you have family members such as parents, siblings, or children, who also have the disease.
  • Using isotretinoin. Drug Isotretinoin (Amnesteem, Claravis, Sotret; formerly called accutane) is a type of medication that is sometimes used to treat acne and acne scars. Several studies have shown that the drug increases the risk factors for contracting ulcerative colitis. But the clarity of the relationship between conditions and isotretinoin has not been determined.

Complications

What are the complications ulcerative colitis?

Ulcerative colitis is a disease condition that can cause complications both inside the digestive system and outside the digestive system. Intestinal complications can include:

  • Intestinal perforation. This is a condition of a hole in the large intestine that is a medical emergency. This condition can cause severe bleeding and stomach pain.
  • Anal fissure. Complications of ulcerative colitis are tears that occur in the lining of the anal canal. If you experience this condition can cause bleeding and pain that can be treated at home.
  • Toxic Megacolon. This is an unusual condition. This condition can cause severe intestinal enlargement. This complication is classified as serious that requires emergency treatment.
  • Colon cancer. After suffering from colitis for about 8 to 10 years, your risk of developing colon cancer increases. It's important to work with a gastroenterologist to schedule regular colon cancer screening

Extra intestinal complications can include:

  • Eye disease. Several eye health conditions, including uveitis, glaucoma, keratopathy, episcleritis, and dry eye, are associated with the condition and treatment of ulcerative colitis.
  • Arthritis. Ulcerative colitis is a condition that can cause complications of this form of arthritis. These include peripheral arthritis, axial arthritis, and rheumatoid arthritis
  • Skin problem. Ulcerative colitis can cause the condition of erythema nodosum and pyoderma gangrenosum.
  • Mouth ulcers. This condition is also called aphthous stomatitis. This is a wound in the lining of the mouth that can occur together with ulcerative colitis.
  • Other symptoms during menstruation. Some women with ulcerative colitis find that the symptoms of pre-menstrual syndrome (PMS) before menstruation causes them to experience diarrhea and pain.

Diagnosis

What are the usual types of tests done to sufferers Ulcerative Colitis?

Before diagnosing the results and treating the symptoms you feel, your doctor will examine you physically, then ask about your family's medical history. The doctor will also generally take blood and urine samples to check for bleeding and infection.

Ulcerative colitis is a condition where the results can be diagnosed by the following tests:

1. Colonoscopy

A colonoscopy is a doctor's way of seeing the overall condition in your large intestine. In ulcerative colitis, the large intestine will have certain characteristics that lead to inflammatory bowel disease (IBD).

There may be inflammation that starts in the rectum or in the last part of the large intestine (sigmoid colon), and inflammation that spreads to the upper part of the intestine. Inflammation can also occur in the walls of the large intestine, the sign will look red and swollen. When examined, the doctor may also cause ulcers (sores) in the lining of the intestine.

During the test, the doctor will do a biopsy that is taking a little tissue in the large intestine. Later the network will be sent to a laboratory for testing. The results of this colonoscopy can help the doctor make a diagnosis of ulcerative colitis.

2. Imaging test

Other imaging tests such as X-ray, barium enema, upper gastrointestinal series, sigmoidoscopy, or upper endoscopy can also be used to diagnose ulcerative colitis. This test will generally produce a picture of your intestinal condition.

3. Other laboratory tests

Blood test

Ulcerative colitis is a condition that can be diagnosed by doing a blood test.

Later, the number of red blood cells and white blood cell count will be counted. This is useful for getting a more complete body picture. Blood tests can also find out if your ulcerative colitis is causing other conditions such as anemia, for example.

Other blood tests can be used to monitor the progress of the disease, especially during inflammation in your intestine flare-ups.

Stool test

Stool tests can generally be used as part of a complete examination of ulcerative colitis. This test is not a determinant test for the diagnosis of ulcerative colitis. However, more is used to find out possible causes of severe stomach pain or bloody diarrhea.

People with inflammatory bowel conditions generally can also have bacterial infections, and tend to be more susceptible to infections. So a stool culture test can be used to confirm or confirm that your symptoms can be caused by a bacterial infection.

Medicines & Medications

The information below is not a substitute for medical advice from a doctor; ALWAYS check yourself with a professional doctor.

What are some examples of treatment that can be done on patients Ulcerative Colitis ?

Ulcerative colitis is a condition whose goal of treatment is to reduce symptoms, control inflammation, and prevent complications. The following are some medicines that doctors will likely prescribe according to their respective conditions and diagnoses:

Anti-inflammatory medicine

Antiinflammatory drugs are drugs that are often used as a treatment for ulcerative colitis, the first step:

1. 5-aminosalicylates: This medicine will be given depending on which part of your large intestine is affected. You can take it orally, or your doctor will prescribe it as an enema and suppository. Some examples of these ulcerative colitis include Azulfidine (sulfasalazine), Asacol HD and Delzicol (mesalamine), Colazal (balsalazide), and Dipentum (olsalazine).

2. Corticosteroid drugs: Prednisone and hydrocortisone drugs will generally be prescribed for those of you who have moderate to severe ulcerative colitis, and also your condition does not respond to other treatments.

The body can not respond to drugs can be caused by side effects, such as weight gain, high blood pressure, mood swings, fluid retention, and osteoporosis.

Immune suppressant drugs (Immune system surpressor)

Ulcerative colitis is a condition that can be given a immune system suppressant drug. These drugs control inflammation by suppressing the immune system's response.

These drugs are often given in combination, such as:

  • Azathioprine. This is the most widely used immunosuppressant drug for the treatment of inflammatory bowel disease. This drug suppresses the immune system by interfering with the body's production of DNA molecules. If you take this medicine, you should continue to consult with your doctor. Your doctor will also check your blood regularly, because side effects can affect the liver and pancreas.
  • Cyclosporine: This is an ulcerative colitis drug that is generally prescribed for people whose bodies have not responded to other medicines well. Cyclosporin is believed to work by suppressing lymphocytes, a type of white blood cell. Because cyclosporine has the potential for serious side effects, it is not prescribed for long-term use.
  • Infliximab, Adalimumab, and Golimumab: These drugs are referred to as tumor necrosis factor inhibitors (TNF). This drug controls the body's abnormal immune response. This drug is usually used in people who have not responded or cannot tolerate other treatments.
  • Vedolizumab: Ulcerative colitis can be treated using this drug. Vedolizumab is a drug that will be given with a condition that does not respond or cannot tolerate other treatments. The drug works by blocking inflammatory cells from getting to the site of inflammation.

Antibiotics

Antibiotics can be prescribed if there is a suspected infection of the large intestine, but people with ulcerative colitis will sometimes not be prescribed antibiotics if there are no symptoms of bacterial infection. This is because antibiotics can cause diarrhea.

Home remedies

What are some forms of lifestyle changes or home remedies that can help me reduce the threat of UC?

The following are forms of a healthy lifestyle and home remedies that can help you deal with ulcerative colitis:

  • Take medicines as instructed by the doctor;
  • Ask your doctor if you can take vitamins, mineral supplements, and iron tablets;
  • Try to do normal physical activity;
  • See your doctor regularly. Colonoscopy examination is very important to monitor periodically how your disease progresses and prevent it from deteriorating into colon cancer.

If you have questions, please consult a professional doctor immediately to get the best medical solution.

Hello Health Group does not provide medical advice, diagnosis, or treatment.

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