Mefenamic Acid – A-Z Medication

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Mefenamic Acid What medication is it?

What’s mefenamic acid for?

Mefenamic acid, or mefenamic acid, is a medication for treating gentle to average ache. Typically used as a medication for toothache, complications, and relieve ache throughout menstruation.

Mefenamic acid or mefenamic acid is called nonsteroidal anti-inflammatory drug (NSAID). This drug can be used to deal with gout assaults.

Mefenamic acid dosage and mefenamic acid negative effects shall be defined additional beneath.

What are the foundations for ingesting mefenamic acid?

Mefenamic acid is normally taken Four occasions a day with a glass of mineral water (Eight ounces or 240 milliliters) or as directed by a health care provider. Don’t lie down for not less than 10 minutes after consuming mefenamic acid.

If abdomen issues happen, take this medication with meals or milk. Don’t take mefenamic acid along with antacids except directed by a health care provider.

Sure antacids might be able to change the quantity of mefenamic acid absorbed by the physique.

Doses are given based mostly on medical situations and response to therapy. To scale back the danger of abdomen bleeding and different negative effects, take mefenamic acid on the lowest dose for a short while.

Don’t enhance your dose, drink usually, or take longer than advisable. Mefenamic acid shouldn’t be taken for greater than 7 days at a time.

When you take mefenamic acid as a primary "need" (not each day), please do not forget that it really works effectively when taken when the primary signal of ache happens. When you look ahead to the indicators to worsen, the medication won’t work correctly.

When you use mefenamic acid for menstrual ache, take your first dose instantly after menstruation or when the ache comes. Often, you solely have to devour it for the primary 2 or Three days throughout your interval.

Inform your physician in case your ache doesn’t lower or worsen or you probably have different new signs.

The way to retailer mefenamic acid?

This drug is finest saved at room temperature, away from direct mild and damp locations. Don’t retailer within the lavatory. Don't freeze it.

Different manufacturers of this drug could have completely different storage guidelines. Observe the storage directions on the product packaging or ask your pharmacist. Preserve all medicines out of the attain of youngsters and pets.

Don’t flush medication in the bathroom or within the sewer except instructed. Discard this product when it has expired or whether it is not wanted.

Seek the advice of your pharmacist or native waste disposal firm about find out how to safely get rid of your product.

Mefenamic Acid Dosage

The knowledge offered just isn’t an alternative to medical recommendation. ALWAYS seek the advice of your physician or pharmacist earlier than beginning therapy.

What’s the dose of mefenamic acid for adults?

The next is the dose of mefenamic acid or mefenamic acid for adults aged 18 years and over:

Mefenamic acid dosage to cope with ache

  • The primary dose is 500 mg. Then, proceed with 250 mg each 6 hours as wanted
  • This medication shouldn’t be taken greater than 7 days.

Mefenamic acid dose for menstrual ache

  • The primary dose is 500 mg. Then, proceed with 250 mg each 6 hours as wanted
  • This medication shouldn’t be taken greater than Three days.

What’s the dose of mefenamic acid for kids?

The next is the dose of mefenamic acid or mefenamic acid for kids:

Mefenamic acid dose for kids 14-18 years

  • The primary dose is 500 mg. Then, proceed with 250 mg each 6 hours as wanted
  • This medication shouldn’t be taken greater than 7 days.

Mefenamic acid or mefenamic acid just isn’t advisable for consumption of youngsters underneath the age of 14 years.

At what dose is mefenamic acid accessible?

Mefenamic acid or mefenamic acid is on the market in capsule kind for ingesting. The content material in 1 capsule is 250 mg.

Unwanted effects of Mefenamic Acid (Mefenamic Acid)

What negative effects might be skilled on account of mefenamic acid?

Unwanted effects of mefenamic acid that aren’t severe however typically happen embody:

  • Nausea, heartburn or stomach ache, diarrhea, constipation, bloating
  • Dizziness, headache, nervousness
  • Itchy pores and skin or rashes
  • Dry mouth
  • Sweating, runny nostril
  • Blurred imaginative and prescient
  • Buzz within the ear

Cease taking mefenamic acid and search medical consideration or name your physician when you’ve gotten severe negative effects:

  • Chest ache, fatigue, shortness of breath, unclear speech, issues with imaginative and prescient or steadiness
  • Black, bloody stools, coughing up blood or vomiting that appears like espresso grounds
  • Hardly ever urinate or in no way
  • Ache, warmth, or bleeding throughout urination
  • Nausea, stomach ache, fever, lack of urge for food, darkish urine, clay-colored stools, jaundice (yellowing of the pores and skin and eyes)
  • Fever, sore throat, and complications, blisters, peeling, and crimson pores and skin rashes
  • Bruising, extreme tingling, numbness, muscle weak point

Not everybody experiences the next negative effects. There could also be some negative effects not talked about above.

In case you have issues about sure negative effects, seek the advice of your physician or pharmacist.

Warnings and Cautions for Mefenamic Acid

What medicines may work together with mefenamic acid?

Drug interactions can change the efficiency of your medicine or enhance the danger of significant negative effects. Not all attainable drug interactions are listed on this doc.

Preserve an inventory of all of the merchandise you employ (together with prescription / nonprescription medicines and natural merchandise) and seek the advice of your physician or pharmacist. Don’t begin, cease or change the dose of any drug with out the physician's approval.

Listed below are the medication which have the potential to trigger interactions with mefenamic acid that you’re consuming:

1. Antihypertensive medication

Taking antihypertensive medication along with mefenamic acid really reduces the impact of reducing blood stress. Examples of medicine included in antihypertension embody:

  • Angiotensin Receptor Blockers, equivalent to valsartan, candesartan, or losartan
  • angiotensin-converting enzyme (ACE) inhibitors, equivalent to captopril, lisinopril, enalapril
  • beta-blocker, equivalent to metoprolol, atenolol, thymolol

2. Diuretic medication

The success of diuretic medication can be lowered if taken along with mefenamic acid. Some examples of diuretic medication are:

  • chlorthalidone
  • torsemide
  • bumetanide

3 Nonsteroidal anti-inflammatory medication (NSAID)

Though mefenamic acid belongs to the class of NSAID medication, you shouldn’t devour mefenamic acid with different NSAIDs.

It is because mefenamic acid mixed with NSAID medication will increase the danger of bleeding and sores in your abdomen. The next are examples of NSAID medication:

  • aspirin
  • ibuprofen
  • naproxen (Aleve, Naprosyn)
  • diclofenac (Voltaren)
  • etodolac (Lodine)
  • phenoprofen (Nalfon)
  • flurbiprofen (Ansaid)
  • indomethacin (Indocin)
  • ketoprofen (Orudis)
  • ketorolac (Toradol)
  • meclofenamate (Meclomen)
  • meloxicam (Mobic)
  • nabumetone (Relafen)
  • piroxicam (Feldene)

4. Blood thinning medication (anticoagulants)

You must also keep away from taking blood-thinning drugs or anticoagulants throughout therapy with mefenamic acid.

5 Selective serotonin reuptake inhibitors (SSRI) and different antidepressants

Medication that have an effect on serotonin within the physique, or SSRIs, additionally trigger interactions with mefenamic acid as a result of it has the potential to trigger severe abdomen bleeding. The next are SSRI medication that must be prevented:

  • citalopram (Celexa)
  • fluoxetine (Prozac, Sarafem, Symbyax)
  • sertraline (Zoloft)
  • duloxetine (Cymbalta)
  • escitalopram (Lexapro)
  • fluvoxamine (Luvox)
  • paroxetine (Paxil)
  • venlafaxine (Effexor)

Taking certainly one of these medication along with mefenamic acid may cause bruising or straightforward bleeding.

6. Different medicines

Different medication also can enhance the danger of drug interactions if taken along with mefenamic acid:

  • cyclosporine (Gengraf, Neoral, Sandimmune)
  • lithium (Eskalith, Lithobid)
  • methotrexate (Rheumatrex, Trexall)
  • steroid (prednisone)
  • lovastatin (Mevacor)
  • ritonavir (Norvir)
  • sulfamethoxazole
  • sulfinpyrazone (Anturane)
  • trimethoprim (Proloprim)
  • zafirlukast (Accolate)

Can meals or alcohol work together with mefenamic acid?

Sure medicines shouldn’t be used when consuming or when consuming sure meals as a result of drug interactions can happen. Smoking or consuming alcohol with sure medication also can trigger interactions to happen.

Focus on your use of medicine with meals, alcohol, or tobacco along with your well being care supplier.

What well being situations can work together with mefenamic acid?

Different well being issues in your physique can have an effect on using this drug. Inform your physician you probably have different well being issues, equivalent to:

1. Bronchial asthma

Roughly 10% of bronchial asthma sufferers could have situations delicate to NSAID medication, together with mefenamic acid. Bronchial asthma sufferers who devour mefenamic acid have the potential to expertise some negative effects equivalent to bronchospasm (seizures) and extreme anaphylactic reactions.

Due to this fact, you probably have bronchial asthma, inform your physician so that you just get a prescription for different, extra appropriate medicines.

2. Edema (fluid retention or swelling within the physique)

In some circumstances, mefenamic acid has the potential to trigger interactions in sufferers who’ve fluid retention or edema. Some ailments associated to this situation are hypertension and coronary heart failure.

Due to this fact, edema victims who take NSAID medication, together with mefenamic acid, ought to get tighter supervision throughout the therapy interval.

3. Digestive issues

Individuals with digestive issues, equivalent to peptic ulcers or irritation of the gut, mustn’t take NSAIDs, together with mefenamic acid.

It is because this drug has the potential to exacerbate present digestive issues, even rising the danger of bleeding within the digestive tract.

4. Kidney illness

Kidney sufferers are additionally not advisable to devour mefenamic acid. This drug has the potential to extend creatinine ranges. Extreme creatinine ranges can set off kidney failure.

5. Liver illness

Mefenamic acid is a drug that has the potential to set off hepatotoxicity, a situation in which there’s an issue or harm to the liver.

Due to this fact, this drug shouldn’t be taken by sufferers who’ve liver issues or ailments.

6. Hypertension

Individuals with hypertension or hypertension must also keep away from mefenamic acid medication. This drug is susceptible to worsening pre-existing hypertension situations.

7. Coronary heart and blood vessel illness

Mefenamic acid medication must also be prevented by sufferers affected by coronary heart and blood vessel issues, equivalent to ischemic coronary heart illness, myocardial infarction, stroke, congestive coronary heart failure, or different vascular ailments.

8. Anemia

Anemia victims usually are not suggested to devour mefenamic acid to keep away from the danger of extreme bleeding within the physique.

Drug Interactions of Mefenamic Acid (Mefenamic Acid)

What must be recognized earlier than utilizing mefenamic acid?

Earlier than taking mefenamic acid, ensure you inform your physician about what drugs you take. That is necessary to forestall interactions, drug poisoning, and harmful negative effects.

Along with medicine, additionally inform your physician or medical employees about any sickness or well being situation that you’re affected by. Mefenamic acid has the potential to set off interactions with sure well being situations.

Inform your physician if you’re pregnant, particularly if you’re within the final month of being pregnant, you intend to turn into pregnant, or breastfeed. When you turn into pregnant whereas utilizing mefenamic acid, name your physician instantly.

If you’ll have surgical procedure, together with dental surgical procedure, inform your physician or dentist that you’re on mefenamic acid

Is mefenamic acid protected for pregnant and lactating girls?

There isn’t any ample analysis on the danger of utilizing mefenamic acid in pregnant or nursing girls.

All the time seek the advice of your physician to contemplate the potential advantages and dangers earlier than utilizing this medication.

These medication fall into the class C danger (could also be dangerous) being pregnant in keeping with US Meals and Medication Administration (FDA)

The next are references to being pregnant danger classes in keeping with the FDA:

  • A = No danger
  • B = No danger in a number of research
  • C = Possibly dangerous
  • D = There’s constructive proof of danger
  • X = Contraindications
  • N = Unknown

It isn’t recognized whether or not mefenamant acid might be absorbed into breast milk or whether or not it’s dangerous to the infant. Don’t use this medication with out telling your physician if you’re breastfeeding.

Mefenamic Acid Overdose

What ought to I do in an emergency or overdose?

In circumstances of emergency or overdose, contact the emergency providers supplier (112) or instantly to the closest hospital emergency division.

Indicators of mefenamic acid overdose embody:

  • Extreme drained
  • Nausea
  • Throws up
  • Abdomen ache
  • Vomiting bleeds and appears like espresso grounds
  • Stools are darkish and bloody
  • Sluggish respiratory
  • Coma (lack of consciousness over a time period)

What ought to I do if I miss a dose?

When you overlook one dose of this medication, take it as quickly as attainable. Nevertheless, when it’s nearing the subsequent dose, skip the missed dose and return to the same old dosing schedule. Don’t double the dose.

Whats up Well being Group doesn’t present medical recommendation, prognosis, or therapy.

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