Trihexyphenidyl – A-Z Drugs


What’s Trihexyphenidyl used for?

Trihexyphenidyl is a drug for treating signs of Parkinson's illness or different actions that can’t be managed, brought on by unwanted effects of sure psychiatric medication (antipsychotics corresponding to chlorpromazine / haloperidol). This drug helps scale back muscle stiffness, extreme sweating, and saliva manufacturing, and helps enhance the power to stroll in folks with Parkinson's.

Trihexyphenidyl belongs to the category of anticlonergic medication that work by blocking sure pure substances (acetylcholine). This drug can not assist with motion issues which can be uncontrolled brought on by tardive dyskinesia, and may truly worsen this situation.

The dose of trihexyphenidyl and the unwanted effects of trihexyphenidyl might be defined additional under.

What are the principles for taking Trihexyphenidyl?

Comply with the principles given by your physician or pharmacist earlier than beginning therapy. When you’ve got questions, seek the advice of your physician or pharmacist.

Trihexyphenidyl is taken often Three to Four instances a day after meals and earlier than going to sleep, or as directed by a physician. Your physician could offer you a low dose to begin with and slowly enhance the dose to get the best dose for you.

Doses are given primarily based on medical circumstances, age, and response to remedy.

When you use the liquid type of this medication, measure your dose with a measuring spoon or measuring system. Don’t use a home spoon as a result of the dosage is wrong.

Take medicine repeatedly to get most outcomes. That can assist you keep in mind, drink on the similar time day-after-day.

Take trihexyphenidyl not less than 1 hour earlier than an antacid containing magnesium, aluminum, or calcium. Depart a niche of not less than 1-2 hours between a dose of trihexyphenidyl and sure diarrhea medication (adsorbent antidiarrheals corresponding to kaolin, pectin, attapulgite).

Take this medication not less than 2 hours after ketoconazole. Anatcid and a few diarrhea medication can forestall trihexyphenidyl from being absolutely absorbed, and this product can forestall ketoconazole from being absolutely absorbed when these merchandise are taken collectively.

When you take trihexyphenidyl to deal with unwanted effects from different medication, your physician could instruct you to take it repeatedly as scheduled or solely when wanted. When you take this medicine for Parkinson's illness, your physician could change your different medicine dosage (for instance, levodopa). Comply with the physician's directions.

There’s a small likelihood that trihexyphenidyl will be addictive. Don’t enhance the dose, enhance the frequency of taking medicine, or take it longer than really helpful. Cease utilizing the drug fully when instructed. Some circumstances will develop into worse when therapy is all of a sudden stopped. Your dose must be decreased slowly

When used for a further time period, this drug could not work effectively and require completely different doses. Discuss to your physician if this medicine stops working. Let your physician know in case your situation stays the identical or worsens.

How is Trihexyphenidyl saved?

This drug is greatest saved at room temperature, away from direct mild and damp locations. Don’t retailer within the rest room. Don't freeze it. Different manufacturers of this drug could have completely different storage guidelines. Observe the storage directions on the product packaging or ask your pharmacist. Preserve all medicines out of the attain of kids and pets.

Don’t flush medication in the bathroom or within the sewer until instructed. Discard this product when it has expired or whether it is now not wanted. Seek the advice of your pharmacist or native waste disposal firm about find out how to safely eliminate your product.


The data offered is just not an alternative choice to medical recommendation. ALWAYS seek the advice of your physician or pharmacist earlier than beginning therapy.

What’s the dose of Trihexyphenidyl for adults?

Trihexyphenidyl dose for extrapyramidal signs in adults:

Preliminary dose of 1 mg as soon as a day, will be elevated to 5-15 mg per day divided into 3-Four doses.

Trihexyphenidyl dose for Parkinson's illness:

  • Preliminary dose: 1 mg / day; the dose will be added 2 mg at intervals of 3-5 days
  • Most dose: 6-10 mg / day in 3-Four separate doses

What’s the dose of Trihexyphenidyl for youngsters?

The dosage for youngsters has not been decided. Seek the advice of along with your physician and pharmacist.

In what dosages is Trihexyphenidyl accessible?

  • Tablets 2 mg; 5 mg
  • Elixir 2 mg / 5 mL

Unintended effects

What unwanted effects will be skilled resulting from Trihexyphenidyl?

Trihexyphenidyl unwanted effects that often happen are:

  • Dry mouth
  • Enlarged eyes or blurred imaginative and prescient
  • Drained or dizzy
  • Problem urinating or constipation
  • Nervous or anxious
  • Abdomen upset
  • Sweat decreases

When you expertise any of the intense unwanted effects under, cease utilizing trihexyphenidyl and search medical assist or contact your physician instantly:

  • Allergic reactions (problem respiration; shut the throat; swelling on the lips, tongue, or face; or spots)
  • Fever
  • Quick or irregular heartbeat
  • Anxious, hallucinations, confused, unable to settle down, hyperactivity, or lack of consciousness
  • Convulsions
  • The attention hurts
  • Rash

Not everybody experiences the next unwanted effects. There could also be some unwanted effects not talked about above. When you’ve got considerations about sure unwanted effects, seek the advice of your physician or pharmacist.

Prevention & Warnings

What ought to be recognized earlier than utilizing Trihexyphenidyl?

In deciding to make use of this drug, the dangers of utilizing the drug should be thought-about rigorously with the advantages gained later. This can be a choice that you just and your physician will make. For this drug, the next it’s worthwhile to take into account:


Inform your physician when you have ever had a special response or allergy to this drug or different medicine. And inform your physician when you have sure allergic reactions, corresponding to meals, coloring, preservatives, or animals. For non-prescription merchandise, rigorously learn the label or substances on the packaging.


There is no such thing as a info accessible concerning the connection between age and the impact of trihexyphenidyl within the pediatric inhabitants. Security and success haven’t but been confirmed.


There is no such thing as a info accessible concerning the connection between age and the impact of trihexyphenidyl in aged sufferers. Nonetheless, older males are likely to have age-related prostrate issues, and all aged sufferers are likely to have issues between the ages with kidney, liver, or coronary heart circumstances. This situation requires consideration or trihexyphenidyl dose adjustment for aged recipient sufferers.

Is Trihexyphenidyl secure for pregnant and lactating ladies?

Being pregnant and breastfeeding: there’s not sufficient info concerning security in using trihexyphenidyl throughout being pregnant and breastfeeding.


What medicines would possibly work together with Trihexyphenidyl?

Drug interactions can change the efficiency of your medicine or enhance the danger of great unwanted effects. Not all potential drug interactions are listed on this doc. Preserve an inventory of all of the merchandise you employ (together with prescription / nonprescription medicines and natural merchandise) and seek the advice of your physician or pharmacist. Don’t begin, cease or change the dose of any drug with out the physician's approval.

Though some medication is probably not used concurrently, in different instances two completely different medication could also be used concurrently even when interplay is feasible. On this case, your physician could change the dose, or different precautions could also be wanted. Inform your physician in case you are utilizing one other prescription or over-the-counter medication.

Use this medication with potassium not really helpful. Your physician could resolve to not deal with you with this medication or change among the medication you’ve gotten used.

Utilizing this drug with one of many following medicines is often not really helpful, however could also be wanted in some instances. If the 2 medication are collectively in a prescription, your physician could change your dose or frequency utilizing one or each of those medication.

  • Morphine
  • Morphine Sulfate Liposome
  • Oxymorphone
  • Umeclidinium

Utilizing this drug with one of many following medication will enhance the danger of sure unwanted effects, however utilizing each medication collectively could also be the perfect therapy for you. If the 2 medication are collectively in a prescription, your physician could change the dose or how typically you employ one or each of those medication.

  • Betel Nut
  • Chlorpromazine
  • Haloperidol
  • Perphenazine

Can meals or alcohol work together with Trihexyphenidyl?

Sure medicines shouldn’t be used when consuming or when consuming sure meals as a result of drug interactions can happen. Consuming alcohol or tobacco with sure medication may trigger interactions to happen. Talk about your use of medicine with meals, alcohol, or tobacco along with your well being care supplier.

What well being circumstances can work together with Trihexyphenidyl?

Different well being issues in your physique can have an effect on using this drug. Inform your physician when you have different well being issues, particularly:

  • Abdomen or intestinal blockage
  • The prostate is enlarged
  • Glaucoma
  • Hypertension (hypertension)
  • Urinary obstruction — Use with warning. Can worsen the situation
  • Kidney sickness
  • Liver illness — Use with warning. The impact will enhance because of the gradual supply of medicine out of the physique


What ought to I do in an emergency or overdose?

In case of emergency or overdose, contact the emergency companies supplier (118/119) or instantly to the closest hospital emergency division.

What ought to I do if I miss a dose?

When you neglect one dose of this medication, take it as quickly as potential. Nonetheless, when it’s nearing the following dose, skip the missed dose and return to the standard dosing schedule. Don’t double the dose.

Good day Well being Group doesn’t present medical recommendation, analysis, or therapy.

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