Trihexyphenidyl: Operate, Dosage, Facet Results, How one can Use – A-Z Medication

What drug is Trihexyphenidyl?

What’s Trihexyphenidyl for?

Trihexyphenidyl is a drug used to deal with signs of Parkinson's illness or different uncontrolled actions brought on by unwanted side effects of sure psychiatric medicine (antipsychotics corresponding to chlorpromazine / haloperidol).

This medicine additionally helps cut back muscle stiffness, extreme sweating, and saliva manufacturing. Not solely that, trihex can also be capable of assist enhance the flexibility to stroll in Parkinson's sufferers.

Trihexyphenidyl belongs to a category of anticlonergic medicine that work by blocking sure pure substances (acetylcholine).

The drug trihexyphenidyl can’t assist with motion issues which can be brought on by uncontrolled tardive dyskinesia. Actually, these medicine could make the situation worse.

What are the principles for taking Trihexyphenidyl?

Comply with the principles given by your physician or pharmacist earlier than beginning remedy with trihexyphenidyl. When you have any questions, seek the advice of your physician or pharmacist.

Trihexyphenidyl is taken normally 3-Four instances a day after meals and at bedtime, or as directed by a physician.

Your physician will in all probability offer you a low dose to begin with, and improve the dose regularly to get the proper dose for you.

The dosage relies in your medical situation, age, and your physique's response to remedy.

In case you are utilizing the liquid type of the drug trihexyphenidyl, measure your dose with a measuring spoon or measuring machine. Don’t use a house tablespoon because the dosage might not be appropriate.

Take medicine recurrently to get most outcomes. That can assist you keep in mind, drink it on the identical time every day.

Take trihexyphenidyl not less than 1 hour earlier than antacids that include magnesium, aluminum, or calcium.

Go away not less than 1-2 hours between doses of trihexyphenidyl and sure diarrhea drugs (adsorbent antidiarrheals corresponding to kaolin, pectin, attapulgite).

Take trihexyphenidyl medicine not less than 2 hours after ketoconazole. Antacids and a few diarrhea drugs can forestall trihexyphenidyl from being totally absorbed, and these merchandise can forestall ketoconazole from being totally absorbed when these merchandise are taken collectively.

In case you are taking trihexyphenidyl to deal with the unwanted side effects of one other drugs, your physician could instruct you to take it recurrently on schedule or solely when wanted.

In case you are taking the drug trihexyphenidyl for Parkinson's illness, your physician could change the dose of your different drugs (for instance, levodopa). Comply with the physician's directions.

There’s a small likelihood that trihexyphenidyl might be addictive. Don’t improve your dose, improve the quantity you are taking your medicine, or take it for longer than really useful.

Cease utilizing the drug utterly when instructed. Even so, some circumstances could turn out to be worse when remedy is stopped immediately. That’s the reason, you could must lower the dosage slowly.

When used for an extra time period, this drug could not work effectively and will require a special dosage. Discuss to your physician if the trihexyphenidyl medicine stops working. Inform your physician in case your situation stays the identical or will get worse.

How is Trihexyphenidyl saved?

Trihexyphenidyl is finest saved at room temperature, away from direct mild and damp locations.

Don't maintain it within the rest room. Don't freeze it. Different manufacturers of this drug could have totally different storage guidelines.

Observe the storage directions on the product package deal or ask your pharmacist. Preserve all medicines away from kids and pets.

Don’t flush medicines down the bathroom or down the drain except instructed to take action. Discard this product when it has expired or when it’s not wanted.

Seek the advice of your pharmacist or native waste disposal firm about how one can safely get rid of your product.

Trihexyphenidyl dosage

The knowledge offered is just not an alternative choice to medical recommendation. ALWAYS seek the advice of your physician or pharmacist earlier than beginning remedy.

What’s the dosage of Trihexyphenidyl for adults?

Trihexyphenidyl dosage for extrapyramidal signs in adults:

The preliminary dose is 1 mg as soon as day by day, might be elevated to 5-15 mg per day divided into 3-Four doses.

Trihexyphenidyl dosage for Parkinson's illness:

  • Preliminary dose: 1 mg / day; the dose could also be elevated by 2 mg in 3-5 day intervals
  • Most dose: 6-10 mg / day in 3-Four separate doses

What’s the dosage of Trihexyphenidyl for youngsters?

The dosage for youngsters has not been decided. Seek the advice of your physician and pharmacist.

In what dosage is Trihexyphenidyl obtainable?

  • 2 mg pill; 5 mg
  • Elixir 2 mg / 5 ml

Trihexyphenidyl unwanted side effects

What unwanted side effects might be skilled on account of Trihexyphenidyl?

The frequent unwanted side effects of trihexyphenidyl are:

  • Dry mouth
  • Enlarged eyeballs or blurred imaginative and prescient
  • Drained or dizzy
  • Problem urinating or constipation
  • Nervous or anxious
  • Abdomen upset
  • Much less sweat

For those who expertise any of the intense unwanted side effects under, cease utilizing trihexyphenidyl and search medical assist or contact your physician straight away:

  • Extreme allergic response (problem respiratory; closing of throat; swelling of the lips, tongue, or face; or freckles)
  • Fever
  • Quick or irregular heartbeat
  • Anxiousness, hallucinations, confusion, restlessness, hyperactivity, or lack of consciousness
  • Convulsions
  • The attention hurts
  • Pores and skin rash

Not everybody experiences the next unwanted side effects. There could also be some unwanted side effects not listed above.

When you have issues about sure unwanted side effects, seek the advice of your physician or pharmacist.

Trihexyphenidyl Drug Warnings and Cautions

What ought to be recognized earlier than utilizing trihex?

Earlier than utilizing this drug, there are a number of issues that want consideration. These items will normally have in mind the quantity of advantages obtained.

Some issues that medical doctors normally think about when deciding to present trihex, embrace:


Inform your physician if in case you have any allergy symptoms to this or another medicine. This shall be his consideration for prescribing this drug or utilizing different medicine.

Additionally inform any allergy symptoms you’ve got, corresponding to to meals, coloring, preservatives, or animals. For over-the-counter merchandise, learn the labels or components on the packaging rigorously.


No info is on the market concerning the connection between age and the impact of trihexyphenidyl within the pediatric inhabitants. Security and success haven’t been confirmed.


No info is on the market concerning the connection between age and the impact of trihexyphenidyl in aged sufferers.

Even so, older males are inclined to have prostate issues as they age, and older folks are inclined to have age-related issues with kidney, liver, or coronary heart circumstances.

This situation requires consideration or an adjustment within the dose of trihexyphenidyl for aged sufferers.

Is Trihexyphenidyl secure for pregnant and lactating girls?

Being pregnant and breastfeeding: there’s inadequate info concerning the security of utilizing trihexyphenidyl throughout being pregnant and breastfeeding.

At all times seek the advice of your physician and let him know your situation, particularly in case you are pregnant and breastfeeding.

Trihexyphenidyl Drug Interactions

What medicines could work together with Trihexyphenidyl?

Drug interactions can change the efficiency of the trihexyphenidyl drug or improve the danger of great unwanted side effects. Not all doable drug interactions are listed on this doc.

Preserve a listing of all of the merchandise you utilize (together with prescription / non-prescription medicine and natural merchandise) and seek the advice of your physician or pharmacist. Don’t begin, cease, or change the dose of any drugs with out your physician's approval.

Though a number of medicine shouldn’t be used concurrently, in some circumstances the 2 medicine which have a threat of interplay could also be prescribed collectively. If that is so, the physician will alter the dose given or the schedule to take the drug to stop opposed drug interactions.

Additionally inform your physician in case you are utilizing different prescription or nonprescription medicine.

Utilizing the drug trihexyphenidyl with potassium not really useful. Your physician could resolve to not deal with you with trihexyphenidyl or change among the medicine you’ve got used.

Utilizing this medicine with any of the next medicine is normally not really useful, however could also be wanted in some circumstances.

  • Morphine
  • Morphine Sulfate Liposome
  • Oxymorphone
  • Umeclidinium

Utilizing the above medicines along with trihex can improve the danger of sure unwanted side effects. Even so, this feature shall be taken with numerous changes by the physician whether it is thought of essentially the most acceptable remedy.

If each medicine are prescribed collectively, your physician could change the dose or how typically you utilize one or each medicine.

  • Betel Nut
  • Chlorpromazine
  • Haloperidol
  • Perphenazine

Can meals or alcohol work together with trihex?

Sure medicine shouldn’t be used when consuming or consuming sure meals as a result of drug interactions can happen.

Consuming alcohol or tobacco with sure medicine may also trigger interactions to happen. Focus on your use of medicine with meals, alcohol, or tobacco along with your well being care supplier.

What well being circumstances could work together with Trihexyphenidyl?

Some other well being downside in your physique can have an effect on using the drug trihexyphenidyl. Inform your physician if in case you have different well being issues, particularly:

  • Blockage of the abdomen or intestines
  • Enlarged prostate
  • Glaucoma
  • Hypertension (hypertension)
  • Urinary blockage — Use with warning. Could make circumstances worse
  • Kidney sickness
  • Liver illness — Use with warning. The impact will improve as a result of slowly leaving the drug from the physique

Trihexyphenidyl overdose

What ought to I do in an emergency or overdose?

In case of an emergency or overdose, contact the emergency providers supplier (112) or instantly to the closest hospital emergency division.

What ought to I do if I miss a dose?

For those who overlook a dose of the drug trihexyphenidyl, take it as quickly as you keep in mind. In case you are near taking the subsequent medicine, ignore the missed dose. Proceed taking the medicine in accordance with the unique schedule. Don’t double your dose on a one-time schedule.

Howdy Well being Group and Howdy Sehat don’t present medical recommendation, prognosis or remedy. Please examine our editorial coverage web page for extra detailed info.

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