What drugs is nifedipine? – A-Z Medication


Generic Title:
Nifedipine


Model:
Calcianta, Farmalat, Nifedin, Adalat, Adalat OROS, Cordalat, Coronipin, Ficor, Inficard, Nifedipine Indo Farma, Nifedipine Landson, Vasdalat Vasdalat / Vasdal and Xepalat.

Use

What's nifedipine for?

Nifedipine is a drug with a perform to stop sure varieties of chest ache (angina). This drug permits you to train extra and scale back the frequency of angina assaults. Nifedipine belongs to a category of medicines often called calcium channel blocker. This drug works by stress-free the blood vessels in order that blood can circulation extra simply. This drugs should be used commonly to be efficient. This drug shouldn’t be used to deal with assaults of chest ache when it happens. Use different medicines (resembling sublingual nitroglycerin) to alleviate chest ache assaults as your physician recommends. Seek the advice of your physician and pharmacist for extra info.

Aged individuals ought to focus on the dangers and advantages of this drug with a health care provider or pharmacist, and different alternate options to nifedipine which are extra widespread (resembling an extended response pill).

OTHER USES: This part accommodates using this drug which isn’t listed on an accepted label, however could also be prescribed by your well being care skilled. Use this drugs for the situations listed under provided that it has been prescribed by your physician and well being skilled.

This drug can be used to deal with sure blood circulation problems (Raynaud's syndrome).

The dose of nifedipine and the negative effects of nifedipine might be defined additional under.

Learn how to use nifedipine?

Use this drugs by taking it based on your physician's recommendation, normally 3 times a day at time for supper or not, as your physician recommends. Swallow this drug in a single piece, don’t grind, chew, or destroy the capsule.

The dosage depends upon well being situations and response to therapy.

Your physician could enhance your dose regularly. Observe the physician's directions nicely.

Keep away from it grapefruit or drink juice grapefruit when utilizing this drugs until your physician or pharmacist permits it. Grapefruit can enhance ranges of sure medicine in your bloodstream. Ask your physician or pharmacist for extra info.

Use this remedy commonly to get the specified outcomes. That will help you keep in mind to make use of it on the identical time each day.

Let your physician know in case your situation is getting worse (for instance, your chest ache is getting worse or is rising in frequency).

How is nifedipine saved?

This drug is finest saved at room temperature, away from direct mild and damp locations. Don’t retailer within the toilet. Don't freeze it. Different manufacturers of this drug could have totally different storage guidelines. Observe the storage directions on the product packaging or ask your pharmacist. Preserve all medicines out of the attain of youngsters and pets.

Don’t flush drugs in the bathroom or within the sewer until instructed. Discard this product when it has expired or whether it is now not wanted. Seek the advice of your pharmacist or native waste disposal firm about the way to safely eliminate your product.

Dose

The data offered will not be an alternative to medical recommendation. ALWAYS seek the advice of your physician or pharmacist earlier than beginning therapy.

What’s the dose of nifedipine for adults?

Dosage for Hypertension in Adults

Preliminary dose:
Prolonged launch tablets: 30 to 60 mg orally as soon as a day
The dose may be elevated regularly each 7 to 14 days.

Dosage for Migraine Prophylaxis in Adults

Preliminary dose:
Prolonged launch tablets: 30 mg orally as soon as a day
Quick capsule launch: 10 mg orally three instances a day

Dosage for Angina Pectoris Prophylaxis in adults

Preliminary dose:
Prolonged launch tablets: 30 to 60 mg orally as soon as a day
Quick capsule launch: 10 mg orally three instances a day
Upkeep dose:
Quick launch capsules: 10 to 30 mg orally three to four instances a day

Dosages for Congenital Coronary heart Failure in Adults

Preliminary dose:
Procardia XL (R): 30 to 60 mg orally as soon as a day
Adalat (R) CC: 30 mg orally as soon as a day

Doses for Untimely Births in Adults

The flexibility of tocolitis from nifedipine has been evaluated in a number of research. Doses used within the examine vary from 10 to 20 mg each 6 to eight hours as wanted and are tolerated to delay supply.

What’s the dose of nifedipine for youngsters?

Doses for Emergency Hypertension in Youngsters

Youngsters:
Quick capsule launch: 0.25 to 0.5 mg / kg / dose (most 10 mg / dose) repeated each four to six hours if wanted
Most dose: 1 to 2 mg / kg / day

Doses for Hypertension in Youngsters

Pill prolonged launch:
Youngsters: 0.25 to 0.5 mg / kg / day divided into 1 to 2 doses; dosage should be titrated for impact.

Most dose: three mg / kg / day as much as 120 mg / day (or 180 mg / day in sure locations)

Doses for Hypertrophic Cardiomyopathy in Youngsters

Youngsters: 0.6 to 0.9 mg / kg / 24 hours divided into three or four doses

In what dose is nifedipine obtainable?

Tablets, ER: 30 mg, 60 mg, 90 mg

Capsules, oral: 10 mg

Unintended effects

What negative effects may be skilled because of nifedipine?

Search emergency assist instantly if you happen to expertise any of the next indicators of an allergic response: rash; problem respiratory; swelling of the face, lips, tongue, or throat.

Contact your physician instantly if you happen to expertise severe negative effects resembling:

  • worsening angina
  • extreme constipation and cramps, extreme belly ache or heartburn, coughing up blood
  • feeling such as you wish to go out
  • really feel problem respiratory, swelling of the arms or ft
  • a quick, quick heartbeat
  • numbness or tingling
  • jaundice (yellowing eyes and pores and skin)
  • chest ache or extreme feeling, ache that radiates to the arms and shoulders, nausea, sweating, feeling unwell

Much less severe negative effects embrace:

  • headache, dizziness
  • drowsiness, feeling drained
  • nausea, constipation, diarrhea, or delicate stomachache
  • sleep problems (insomnia)
  • delicate itching or rashes
  • joint ache, cramps within the legs
  • really feel heat, tingling, or redness in your pores and skin
  • extra frequent urination

Not everybody experiences the above negative effects. There could also be some negative effects not talked about above. When you have considerations about sure negative effects, seek the advice of your physician or pharmacist.

Prevention & Warnings

What ought to be recognized earlier than utilizing nifedipine?

Earlier than utilizing Nifedipine,

  • inform your physician when you have an allergy to nifedipine, different medicines, or any composition within the nifedipine product that’s prescribed. Ask your pharmacist for an inventory of compositions
  • inform your physician and pharmacist what prescription and prescription medicines, nutritional vitamins, remedies and natural merchandise you’re taking or plan to take. Be sure you point out the next medicines: acarbose (Prandase, Precose); anticoagulants (‘blood thinners’) resembling warfarin (Coumadin, Jantoven); antifungals resembling fluconazole (Diflucan), itraconazole (Sporanox), and ketoconazole (Nizoral); beta blockers resembling atenolol (Tenormin), labetalol (Trandate), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), propranolol (Inderal), and timolol (Blocadren); carbamazepine (Carbatrol, Epitol, Tegretol); cimetidine (Tagamet); digoxin (Lanoxin, Lanoxicaps); diltiazem (Cardizem); doxazosin (Cardura); erythromycin (E.E.S., E-Mycin, Erythrocin); fentanyl (Actiq, Duragesic, Fentora, Sublimaze); flecainide (Tambocor); HIV protease inhibitors resembling amprenavir (Agenerase), atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), and ritonavir (Norvir, in Kaletra); metformin (Glucophage); nefazodone; phenobarbital (Luminal); phenytoin (Dilantin, Diphenylan Sodium); quinidine (Quinidex); quinupristin and dalfopristin (Synercid); rifampin (Rifadin, in Rifamate, in Rifater, Rimactane); rifapentine (Priftin); tacrolimus (Prograph); valproic acid (Depakene, Depakote); and verapamil (Calan, Covera, Isoptin, Verelan). Your physician might have to alter the dosage of remedy or watch you for negative effects
  • inform your physician concerning the natural merchandise you might be utilizing, particularly St. John’s Wort.
  • inform your physician when you have or have had a narrowing or blockage of the digestive system or different situations that trigger slower meals digestion; or coronary heart, liver, or kidney illness. Additionally inform your physician when you have skilled a myocardial an infection up to now 2 weeks
  • inform your physician if you’re pregnant, planning a being pregnant, breastfeeding. If you happen to grow to be pregnant whereas utilizing nifedipine, contact your physician
  • Seek the advice of your physician concerning the security of utilizing nifedipine capsules if you’re aged 65 years and over. The aged should not suggested to make use of nifedipine capsules as a result of they aren’t as secure as different medicine that can be utilized to deal with the identical situation.
  • if you happen to do surgical procedure, together with dental surgical procedure, inform your physician or dentist that you’re utilizing nifedipine
  • Ask your physician concerning the security of utilizing alcoholic drinks when utilizing nifedipine. Alcohol can worsen the negative effects of nifedipine.

Is nifedipine secure for pregnant and lactating girls?

There isn’t any ample analysis on the dangers of utilizing this drug in pregnant or nursing girls. At all times seek the advice of your physician to think about the potential advantages and dangers earlier than utilizing this drugs. This drug is included within the class C being pregnant threat based on the US Meals and Medication Administration (FDA)

The next are references to being pregnant threat classes based on the FDA:

  • A = No threat,
  • B = No threat in some research,
  • C = Perhaps dangerous,
  • D = There may be constructive proof of threat,
  • X = Contraindications,
  • N = Unknown

Nifedipine can go via breast milk and may be dangerous to nursing infants. Let your physician know if you’re breastfeeding.

Interplay

What medicines would possibly work together with nifedipine?

Drug interactions can change the way in which medicine work or enhance your threat for severe negative effects. This doc doesn’t embrace all drug interactions that may happen. Preserve an inventory of the merchandise you employ (together with prescription / nonprescription medicines and natural merchandise) and inform your physician and pharmacist. Don’t begin, cease or change the dose of any drugs with out your physician's information.

Earlier than utilizing this drugs, inform your physician or pharmacist about all of the prescription and non-prescription medicine and natural merchandise that you’re utilizing, particularly these containing:

Phenytoin, quinidine, tacrolimus.

Different medicine can have an effect on the elimination of nifedipine out of your physique, which may have an effect on the efficiency of nifedipine. Examples embrace cimetidine, azole antifungals (resembling triraconazole), macrolide antibiotics (resembling erythromycin), rifamycins (such asrifabutin), St. John’s wort, medicine used to deal with seizures (resembling carbamazepine), and others.

Verify the labels of all of your medicines (resembling chilly and cough merchandise, food plan medicine) as a result of they will comprise components that may enhance coronary heart charge and worsen chest ache (together with caffeine, pseudoephedrine, and phenylephrine). Ask your pharmacist about utilizing this product safely.

Cimetidine is a non-prescription drug that’s used to deal with extra abdomen acid, as a result of cimetidine can work together with nifedipine, ask the pharmacist about different merchandise that may deal with extra abdomen acid.

Can meals or alcohol work together with nifedipine?

Sure medicines shouldn’t be used when consuming or when consuming sure meals as a result of drug interactions can happen. Consuming alcohol or tobacco with sure medicine may also trigger interactions to happen. Focus on your use of medicine with meals, alcohol, or tobacco along with your well being care supplier.

What well being situations can work together with nifedipine?

Different well being issues can have an effect on using this drug. Let your physician know when you have different well being issues, particularly:

  • aortic stenosis (narrowing of the valve to the guts)
  • heavy digestive tract blockage
  • congenital coronary heart failure
  • coronary heart assault
  • hypotension (low blood strain) – use with warning. Can enhance severe negative effects.
  • cardiogenic shock (shock brought on by a coronary heart assault) – shouldn’t be utilized in sufferers with this situation
  • galactose intolerance (uncommon hereditary illness)
  • Lapp lactase deficiency (uncommon hereditary illness) —the prolonged launch pill of this drug accommodates lactose (milk sugar), and shouldn’t be given to sufferers with this situation
  • kidney drawback
  • liver issues (together with cirrhosis) – use with warning. The impact of nifedipine may be elevated because of slower drug launch from the physique.

Overdose

What ought to I do in an emergency or overdose?

In circumstances of emergency or overdose, contact the native emergency companies supplier (112) or instantly to the closest hospital emergency division.

Signs of overdose may be signs of hypoglycemia and the next:

  • dizzy
  • quick coronary heart charge
  • pores and skin is purple and feels heat
  • fidgety
  • nausea
  • throw up
  • swelling of the arms, ft, ankles or calves
  • blurred imaginative and prescient
  • handed out

What ought to I do if I miss a dose?

If you happen to overlook one dose of this drugs, take it as quickly as doable. However when it’s nearing the following dose, skip the missed dose and return to the standard dosage schedule. Don’t double the dose.

Hey Well being Group doesn’t present medical recommendation, prognosis, or therapy.

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