What medication is Trihexyphenidyl? – A-Z Medication

Generic Identify:

Arkine, Hexymer, Parkinal, Artane, Trihexyphenidyl Indo Farma and trihexyphenidyl-drug-function-parkinsonism.


What’s Trihexyphenidyl used for?

Trihexyphenidyl is a drug for treating signs of Parkinson's illness or different actions that can not be managed, attributable to unwanted side effects of sure psychiatric medication (antipsychotics akin to chlorpromazine / haloperidol). This drug helps scale back muscle stiffness, extreme sweating, and saliva manufacturing, and helps enhance the flexibility to stroll in folks with Parkinson's.

Trihexyphenidyl belongs to the category of anticlonergic medication that work by blocking sure pure substances (acetylcholine). This drug can’t assist with the issue of out-of-control actions attributable to tardive dyskinesia, and may truly worsen this situation.

The dose of trihexyphenidyl and the unwanted side effects of trihexyphenidyl shall be defined additional beneath.

What are the principles for taking Trihexyphenidyl?

Comply with the principles given by your physician or pharmacist earlier than beginning therapy. If in case you have questions, seek the advice of your physician or pharmacist.

Trihexyphenidyl is taken normally Three to Four instances a day after meals and earlier than going to sleep, or in keeping with physician's instructions. Your physician could provide you with a low dose to start out with and slowly enhance the dose to get the suitable dose for you.

Doses are given based mostly on medical circumstances, age, and response to remedy.

For those who use the liquid type of this medication, measure your dose with a measuring spoon or measuring gadget. Don’t use a home spoon as a result of the dosage is inaccurate.

Take treatment frequently to get most outcomes. That can assist you bear in mind, drink on the similar time every single day.

Take trihexyphenidyl at the least 1 hour earlier than an antacid containing magnesium, aluminum, or calcium. Go away a spot of at the least 1-2 hours between a dose of trihexyphenidyl and sure diarrhea medication (adsorbent antidiarrheals akin to kaolin, pectin, attapulgite).

Take this medication at the least 2 hours after ketoconazole. Anatcid and a few diarrhea medication can stop trihexyphenidyl from being totally absorbed, and this product can stop ketoconazole from being totally absorbed when these merchandise are taken collectively.

For those who take trihexyphenidyl to deal with unwanted side effects from different medication, your physician could instruct you to take it frequently as scheduled or solely when wanted. For those who take this treatment for Parkinson's illness, your physician could change your different treatment dosage (for instance, levodopa). Comply with the physician's directions.

There’s a small likelihood that trihexyphenidyl will be addictive. Don’t enhance the dose, enhance the frequency of taking treatment, or take it longer than advisable. Cease utilizing the drug utterly when instructed. Some circumstances will turn out to be worse when therapy is instantly stopped. Your dosage must be decreased slowly

When used for a further time period, these medication could not work nicely and require completely different doses. Speak to your physician if this treatment stops working. Let your physician know in case your situation stays the identical or worsens.

How is Trihexyphenidyl saved?

This drug is finest saved at room temperature, away from direct gentle and damp locations. Don’t retailer within the rest room. Don't freeze it. Different manufacturers of this drug could have completely different storage guidelines. Observe the storage directions on the product packaging or ask your pharmacist. Preserve all medicines out of the attain of youngsters and pets.

Don’t flush medication in the bathroom or within the sewer until instructed. Discard this product when it has expired or whether it is now not wanted. Seek the advice of your pharmacist or native waste disposal firm about tips on how to safely get rid of your product.


The data supplied is just not an alternative to medical recommendation. ALWAYS seek the advice of your physician or pharmacist earlier than beginning therapy.

What’s the dose of Trihexyphenidyl for adults?

Trihexyphenidyl dose for extrapyramidal signs in adults:

Preliminary dose of 1 mg as soon as a day, will be elevated to 5-15 mg per day divided into 3-Four doses.

Trihexyphenidyl dose for Parkinson's illness:

  • Preliminary dose: 1 mg / day; the dose will be added 2 mg at intervals of 3-5 days
  • Most dose: 6-10 mg / day in 3-Four separate doses

What’s the dose of Trihexyphenidyl for kids?

The dosage for kids has not been decided. Seek the advice of along with your physician and pharmacist.

In what dosages is Trihexyphenidyl accessible?

  • Tablets 2 mg; 5 mg
  • Elixir 2 mg / 5 mL

Negative effects

What unwanted side effects will be skilled because of Trihexyphenidyl?

Trihexyphenidyl unwanted side effects that normally happen are:

  • Dry mouth
  • Enlarged eyes or blurred imaginative and prescient
  • Drained or dizzy
  • Problem urinating or constipation
  • Nervous or anxious
  • Abdomen upset
  • Sweat decreases

For those who expertise any of the intense unwanted side effects beneath, cease utilizing trihexyphenidyl and search medical assist or contact your physician instantly:

  • Allergic reactions (issue respiration; shut the throat; swelling on the lips, tongue, or face; or spots)
  • Fever
  • Quick or irregular heartbeat
  • Anxious, hallucinations, confused, unable to settle down, hyperactivity, or lack of consciousness
  • Convulsions
  • The attention hurts
  • Rash

Not everybody experiences the next unwanted side effects. There could also be some unwanted side effects not talked about above. If in case you have issues about sure unwanted side effects, seek the advice of your physician or pharmacist.

Prevention & Warnings

What needs to be identified earlier than utilizing Trihexyphenidyl?

In deciding to make use of this drug, the dangers of utilizing the drug should be thought of fastidiously with the advantages gained later. This can be a determination that you simply and your physician will make. For this drug, the next it’s good to think about:


Inform your physician you probably have ever had a distinct or allergic response to this or different treatment. And inform your physician you probably have sure allergic reactions, akin to meals, coloring, preservatives, or animals. For non-prescription merchandise, fastidiously learn the label or components on the packaging.


There isn’t any info accessible relating to the connection between age and the impact of trihexyphenidyl within the pediatric inhabitants. Security and success haven’t but been confirmed.


There isn’t any info accessible relating to the connection between age and the impact of trihexyphenidyl in aged sufferers. Nevertheless, aged males are likely to have age-related prostrate issues, and all aged sufferers are likely to have issues between the ages with kidney, liver, or coronary heart circumstances. This situation requires consideration or trihexyphenidyl dose adjustment for aged recipient sufferers.

Is Trihexyphenidyl secure for pregnant and lactating ladies?

Being pregnant and breastfeeding: there may be not sufficient info relating to security in using trihexyphenidyl throughout being pregnant and breastfeeding.


What medicines would possibly work together with Trihexyphenidyl?

Drug interactions can change the efficiency of your treatment or enhance the danger of significant unwanted side effects. Not all attainable drug interactions are listed on this doc. Preserve an inventory of all of the merchandise you utilize (together with prescription / nonprescription medicines and natural merchandise) and seek the advice of your physician or pharmacist. Don’t begin, cease or change the dose of any drug with out the physician's approval.

Though some medication might not be used concurrently, in different circumstances two completely different medication could also be used concurrently even when interplay is feasible. On this case, your physician could change the dose, or different precautions could also be wanted. Inform your physician in case you are utilizing one other prescription or over-the-counter medication.

Use this medication with potassium not advisable. Your physician could determine to not deal with you with this medication or change a number of the medication you might have used.

Utilizing this drug with one of many following medicines is normally not advisable, however could also be wanted in some circumstances. If the 2 medication come collectively in a prescription, your physician could change your dose or frequency utilizing one or each of those medication.

  • Morphine
  • Morphine Sulfate Liposome
  • Oxymorphone
  • Umeclidinium

Utilizing this drug with one of many following medication will enhance the danger of sure unwanted side effects, however utilizing each medication collectively could also be the perfect therapy for you. If the 2 medication are collectively in a prescription, your physician could change the dose or how usually you utilize one or each of those medication.

  • Betel Nut
  • Chlorpromazine
  • Haloperidol
  • Perphenazine

Can meals or alcohol work together with Trihexyphenidyl?

Sure medicines shouldn’t be used when consuming or when consuming sure meals as a result of drug interactions can happen. Consuming alcohol or tobacco with sure medication may also trigger interactions to happen. Talk about your use of medicine with meals, alcohol, or tobacco along with your well being care supplier.

What well being circumstances can work together with Trihexyphenidyl?

Different well being issues in your physique can have an effect on using this drug. Inform your physician you probably have different well being issues, particularly:

  • Abdomen or intestinal blockage
  • The prostate is enlarged
  • Glaucoma
  • Hypertension (hypertension)
  • Urinary obstruction — Use with warning. Can worsen the situation
  • Kidney sickness
  • Liver illness — Use with warning. The impact will enhance because of the sluggish supply of medicine out of the physique


What ought to I do in an emergency or overdose?

In circumstances of emergency or overdose, contact the emergency companies supplier (118/119) or instantly to the closest hospital emergency division.

What ought to I do if I miss a dose?

For those who overlook one dose of this medication, take it as quickly as attainable. Nevertheless, when it’s nearing the subsequent dose, skip the missed dose and return to the same old dosage schedule. Don’t double the dose.

Howdy Well being Group doesn’t present medical recommendation, prognosis or therapy.

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