Categories: Medicine A-Z

Amlodipine – A-Z Medicine


What is Amlodipine used for?

Amlodipine is a calcium channel blockers drug to reduce high blood pressure. The medicine for hypertension works by entering certain tissues and arteries. Then it flows to the heart so it works very effectively to lower blood pressure.

This antihypertensive drug can be used as a combination of other drugs to treat high blood pressure or be used independently. By taking this medication, it means that patients can reduce high blood pressure which is owned while helping to prevent strokes, heart attacks, and kidney problems.

Amlodipine is also used to prevent certain types of chest pain (angina). This high blood pressure medication can help improve your ability to exercise and reduce the frequency of angina attacks.

However, this medication for hypertension should not be used to treat attacks of chest pain when the condition occurs. Use other drugs such as sublingual nitroglycerin to relieve chest pain attacks as directed by your doctor.

What are the rules for using Amlodipine?

Take these medications to reduce high blood pressure with or without food as directed by your doctor. Usually taken once a day. Dosing is based on medical conditions and your response to treatment. Your doctor may gradually increase your dose. Therefore, follow the doctor's instructions carefully.

Use this antihypertensive medication regularly to get its benefits. To help you remember when to take your medication, be sure to take it at the same time. It is important to continue taking this medicine even if you are feeling well. The reason is, most people with high blood pressure do not feel sick.

If used for angina, this drug must be taken regularly to be effective. Tell your doctor if your condition does not improve or if it worsens, for example:

  • Your blood pressure reading remains high or increased
  • Chest pain continues or worsens

Follow the rules given by your doctor or pharmacist before starting treatment. If you have questions, consult your doctor or pharmacist.

How to store Amlodipine?

This hypertension medication is best stored at room temperature, so it must be kept away from direct light and damp places. Do not store in the bathroom or freeze.

Other brands of this drug may have different storage rules. For that, pay attention to storage instructions on product packaging or ask your pharmacist. Keep all medicines out of reach of children and pets, so that the condition is not damaged or eaten by children.

Do not flush medicine in the toilet or in the sewer unless instructed. Discard this product when it has expired or if it is no longer needed. Always consult your local pharmacist or waste disposal company about how to safely dispose of your product.


The information provided is not a substitute for medical advice. ALWAYS consult a doctor or pharmacist before starting treatment.

What is the dose of Amlodipine for adults?

The usual adult dose for hypertension

Initial dose: 5 mg orally once a day

Maintenance dose: 5-10 mg orally once a day. Vulnerable patients can be started on 2.5 mg orally once a day.

The usual adult dose for angina pectoris

Stable chronic or vasospastic angina, or documented angiographic coronary artery disease in patients without heart failure or ejection fraction less than 40%:

5-10 mg orally once a day. Most patients with stable angina or chronic vasospastic need 10 mg for adequate effects. In clinical studies, most patients with coronary artery disease need 10 mg.

The usual adult dose for coronary artery disease

Stable chronic or vasospastic angina, or documented angiographic coronary artery disease in patients without heart failure or ejection fraction less than 40%:

5-10 mg orally once a day. Most patients with stable angina or chronic vasospastic need 10 mg for adequate effects. In clinical studies, most patients with coronary artery disease need 10 mg.

What is the dose of Amlodipine for children?

The usual children's dose for hypertension

6-17 years: 2.5-5 mg orally once a day. Note: Doses of more than 5 mg daily have not been studied in pediatric patients.

In what dosages and preparations is Amlodipine available?

This drug is only available in tablet form, including doses of 2.5 mg, 5 mg, and 10 mg. so you need a glass of water to swallow easily. If you cannot take this medicine, consult your doctor about other easy ways to take medicine.

Side effects

What side effects might occur due to Amlodipine?

Generally these high blood pressure-lowering drugs cause drowsiness. This is the mildest side effect. Stop using amlodipine and contact your doctor if you have any of the following serious side effects:

  • Swelling in the hands, ankles or feet
  • Palpitations or fluttering in the chest; or
  • Chest pain or severe feeling, pain spreading to the arm or shoulder, nausea, sweating, general feeling of pain

Less serious amlodipine side effects may include:

  • Headache
  • Dizzy, sleepy
  • Feeling tired
  • Stomach ache; or
  • Flushing (warmth, redness on the skin, or tingling sensations)
  • Lost consciousness

Not everyone experiences the following side effects. There may be some side effects not mentioned above. If you have concerns about certain side effects, consult your doctor or pharmacist.

If you are taking antihypertensive drugs for the first time or increasing the dose and feeling chest pain is getting worse, you are likely to have a heart attack. Stop using it immediately if you experience this. In addition to chest pain, other heart attack symptoms that you should be aware of include:

  • Hard to breathe
  • Upper body aches and aches
  • The body feels tired and continues to sweat cold
  • Nausea and dizziness

Prevention & Warnings

What must be known before using Amlodipine?

Before using this high blood pressure medication, make sure the following:

You have allergies

Tell your doctor and pharmacist if you are allergic to amlodipine, other drugs, or any ingredient in this antihypertensive medication tablet. Ask the pharmacist what the ingredients are.

Allergy symptoms from the use of this hypertension medication, include:

  • Difficulty breathing
  • Itchy body
  • Swelling of the face, lips, throat or tongue
  • Feeling to faint
  • Nausea and vomiting
  • The body continues to sweat

Don't take this medicine again if you have had an allergic reaction to it. Instead of treating hypertension, continuing to use this drug can even cause fatal problems, such as death.

Moderate or will use other drugs

Tell your doctor and pharmacist about prescription drugs and non-prescription drugs, vitamins, nutritional supplements, and herbal products that you use or will use. Be sure to let them know if you are taking one of these medicines, such as:

Heart medicine

Using diltiazem with amlodipine can increase the level of amlodipine in your body. This can cause more side effects.

Antifungal drugs

Taking amlodipine with antifungal drugs can increase the level of amlodipine in your body. This can cause more side effects or more severe side effects. For example, these drugs include:

  • Ketoconazole
  • Itraconazole
  • Vorikonazol
  • Antibiotic

Medication for erectile problems

Taking high blood medications with drugs for erection problems can increase the risk of low blood pressure (hypotension), including:

  • Sildenafil
  • Tadalafil
  • Avanafil
  • Vardenafil
  • Cholesterol medication

Medications that control the immune system

Taking high blood pressure medications with these drugs can double the dosage content. This can cause more side effects. For example, these drugs, namely:

Have certain conditions

If you have any condition, always tell your doctor. The following medical conditions that you must tell your doctor, are:

Liver disease

This antihypertensive medication is processed in your liver. If liver function does not work properly, the drug will not be processed effectively. That means, the effects of the drug will last longer in the body. This puts you at risk of more side effects. If you have liver problems, ask your doctor to reduce the dose of the drug.

Heart disease

If you have heart problems, such as narrowing of the arteries, medications can increase some of the risk of health problems. This drug can cause chest pain to get worse, heart attack, or very low blood pressure if you increase the dose. So, it is very important to inform your doctor about your health condition.

Is Amlodipine safe for pregnant or breastfeeding women?

There is no adequate research on the risks of using this drug in pregnant or nursing women. Always consult your doctor to consider the potential benefits and risks before using this medicine. This drug is included in the risk of pregnancy category C according to the US Food and Drugs Administration (FDA).

The following are references to pregnancy risk categories according to the FDA:

  • A = No risk
  • B = No risk in several studies
  • C = Maybe risky
  • D = There is positive evidence of risk
  • X = Contraindications
  • N = Unknown


What medicines might interact with Amlodipine?

Drug interactions can change the performance of your medication or increase the risk of serious side effects. Not all possible drug interactions are listed in this document.

Keep a list of all the products you use (including prescription / nonprescription medicines and herbal products) and consult your doctor or pharmacist. Do not start, stop or change the dose of any drug without the doctor's approval

Tell your doctor about all other medicines you use, especially:

  • Simvastatin (Zocor, Simcor, Vytorin); or
  • Any heart medication or other blood pressure

Can food or alcohol interact with Amlodipine?

Certain medicines should not be used when eating or when eating certain foods because drug interactions can occur.

Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with Amlodipine?

Other health problems in your body can affect the use of this drug. Let your doctor know if you have other health problems, such as:

  • Angina (chest pain)
  • Acute heart attack
  • Heart disease or blood vessel disease (for example, coronary artery disease)
  • Hypotension (low blood pressure) – Use with caution. Might make conditions worse
  • Heart disease or other heart problems (for example, aortic stenosis) – Use with caution. The blood pressure-lowering effect of this drug can be increased
  • Liver disease – Use with caution. The effect can be enhanced due to the slower cleansing of the drug from the body


What should I do in an emergency or overdose?

In case of emergency or overdose, contact your local emergency services provider (118/119) or immediately to the nearest hospital emergency department.

Symptoms of an overdose may include:

  • Dizzy
  • Passed out
  • Fast heartbeat

What should I do if I miss a dose?

If you forget one dose of this medicine, take it as soon as possible. But when it is nearing the next dose, skip the missed dose and return to the usual dosage schedule. Do not double the dose without the knowledge of the doctor.

What rules do you need to obey when using Amlodipine?

Use medication as directed

Amlodipine oral tablets are used for long-term treatment. However, it will pose a serious risk if you use it without supervision from a doctor.

Stop treatment if it causes unpleasant symptoms

The use of drugs must be monitored by a doctor. Because, not everyone can use this medicine smoothly. If it causes unusual symptoms, talk to your doctor immediately.

Don't skip or stop taking medicine without a doctor's direction

Hypertension is not like a cold that actually goes away from the body. Once you have this disease, you will continue to have it. However, you can live a healthy life if you take medicine regularly and apply a healthy life. So, don't try to stop taking medicine without permission from the doctor or accidentally miss it.

Do not take more than the dose

The last rule you must obey is not to use drugs over doses. Because the drugs that have been given by doctors have been adjusted to the age, body condition, and how severe the disease you have. If you take more than the dose, you may experience low blood pressure.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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