Medroxyprogesterone: Perform, Dosage, Aspect Results, Find out how to Use – A-Z Medication

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Medroxyprogesterone What Drug?

What’s medroxyprogesterone for?

Medroxyprogesterone is a hormonal contraceptive that may be given orally (taken by mouth) or by injection. This drug works by changing the hormone progesterone as a result of the physique can’t produce sufficient of this hormone.

Normally this drug is used to deal with uterine bleeding because of hormonal imbalance, secondary amenorrhea, and endometriosis. In addition to, this drug can also be used as a mixture hormone alternative remedy utilizing estrogen to scale back menopausal signs (for instance, sizzling flashes).

This drug cannot be purchased anyplace, since you want a health care provider's prescription to make up for it.

How is medroxyprogesterone used?

Take medroxyprogesterone precisely as prescribed by your physician or as prescribed on the prescription label. In case you don't actually perceive the right way to use it, don't hesitate to ask on to a health care provider or pharmacist.

This drug can be utilized orally (taken orally) or as an injection. Take the medication based on the advisable dosage. Don’t try to extend or lower the dose of the drug as this may improve the unwanted effects.

Ask your physician how lengthy you need to use this treatment. As a result of, the dose and length of use of this drug could also be completely different for every individual. The physician will decide the well being situation and the affected person's response to therapy.

Giving medicine by injection ought to be finished beneath the supervision of a health care provider. That is to keep away from undesirable unwanted effects afterward. After the drug has been efficiently injected, it’s possible you’ll really feel a sensation of ache and redness on the injection web site.

Inform your physician in case your situation doesn’t enhance or if it will get worse.

How is medroxyprogesterone saved?

Medroxyprogesterone is finest saved at room temperature, away from direct mild and damp locations. Don't hold it within the toilet. Don't freeze it.

Different manufacturers of this drug could have completely different storage guidelines. Observe the storage directions on the product bundle or ask your pharmacist. Maintain all medicines away from youngsters and pets.

Don’t flush medicines down the bathroom or down the drain until instructed to take action. Discard this product when it has expired or when it’s now not wanted.

Seek the advice of your pharmacist or native waste disposal firm about the right way to safely get rid of your product.

Medroxyprogesterone dosage

The data offered is just not an alternative choice to medical recommendation. ALWAYS seek the advice of your physician or pharmacist earlier than beginning therapy.

What’s the dose of medroxyprogesterone for adults?

The dosage for every individual could also be completely different. The dosage of medicine is normally adjusted based on the affected person's age, general well being situation, and their response to therapy.

You’ll want to all the time seek the advice of a health care provider or pharmacist earlier than taking any kind of treatment. That is to make sure that you’re taking the drug based on the advisable dosage.

What’s the dose of medroxyprogesterone for youngsters?

There isn’t any particular dosage requirement for youngsters. The dosage of medicine for youngsters is normally adjusted based on their weight, well being situation, and their response to therapy.

This drug will be harmful for youngsters if used improperly. Subsequently, seek the advice of your physician or pharmacist for extra info.

In what dosage is medroxyprogesterone out there?

This drug is offered within the type of injectable liquid and ingesting tablets.

Medroxyprogesterone unwanted effects

What are the unwanted effects of medroxyprogesterone?

Principally, all medicine have the potential to trigger unwanted effects from gentle to extreme, together with this drug. A few of the most typical unwanted effects that folks complain about after utilizing medroxyprogesterone embody:

  • Nausea
  • The abdomen recurs
  • Delicate complications
  • Sleepy
  • Abdomen ache
  • The vagina feels just a little itchy
  • Leucorrhoea
  • Menstrual cycle modifications
  • Weight achieve / loss
  • Sizzling flashes within the physique accompanied by redness of the pores and skin (sizzling flashes)
  • Muscle and joint ache
  • Ache within the breast
  • Feeling weak and powerless
  • Erratic temper swings equivalent to irritability
  • Zits happens
  • Rash or swelling on the injection web site

Though much less frequent, a number of the unwanted effects beneath shouldn’t be underestimated. You need to examine together with your physician instantly for those who expertise a number of of the next unwanted effects:

  • Uncommon vaginal bleeding
  • Vital temper swings, equivalent to melancholy and nervousness
  • Swelling of the arms, toes and different components of the physique
  • Urinating is painful
  • A lump seems within the breast
  • There are black patches on the pores and skin or face (melasma)
  • Yellowing of the eyes and pores and skin (jaundice)
  • The physique feels so drained that it’s tough to do numerous actions

A really severe allergic response (anaphylactic shock) to this drug is reported to be fairly uncommon. Nonetheless, search medical consideration instantly for those who see or really feel indicators equivalent to:

  • Crimson rash
  • Itching partially or everywhere in the physique
  • Swelling of the face, tongue and throat
  • Extreme dizziness
  • Exhausting to breathe
  • It's arduous to breath

Not everybody experiences the above unwanted effects. There could also be some unspecified unwanted effects. If in case you have considerations about sure unwanted effects, seek the advice of your physician or pharmacist.

Medroxyprogesterone Drug Warnings and Cautions

What ought to be identified earlier than utilizing medroxyprogesterone?

There are a number of issues you could know and do earlier than utilizing medroxyprogesterone, together with:

  • Inform me medical doctors and pharmacists for those whoa allergic to medroxyprogesterone or different contraceptive medicine.
  • Inform your physician and pharmacist about all of the medicines you’re taking and will likely be taking recurrently each day. Whether or not it's pharmaceuticals, non-prescription medicine, to natural medicines. Your physician may have to alter the dose of your treatment or monitor you rigorously to forestall sure unwanted effects.
  • Inform your physician and pharmacist in case you have a historical past of breast most cancers or different issues affecting the feminine organs. For instance, vaginal bleeding for no obvious purpose and missed abortions (when the fetus dies within the womb however is just not expelled from the physique).
  • Inform your physician and pharmacist in case you have a historical past of coronary heart illness, diabetes, stroke, migraine, melancholy, and impaired liver and kidney operate.
  • Inform your physician in case you are pregnant, are within the means of turning into pregnant, or breastfeeding. Don’t breastfeed whereas taking this medication. In case you develop into pregnant whereas taking the medication, contact your physician.
  • Inform your physician if you’ll have or have lately had surgical procedure, together with dental surgical procedure. Ensure you inform your physician or dentist that you’re taking this medication.

One other factor that must be finished

This treatment has the unwanted effects of lightheadedness and drowsiness. It’s higher to not drive or function equipment till the impact of the drug is totally gone.

There are reviews that reveal that this drug can improve the danger of uterine most cancers. Now, to assist stop this, your physician could prescribe medroxyprogesterone with different medicine that include progestins.

This drug can also be identified to extend the danger of coronary heart assault, blood clots, or stroke. This danger happens when the drug is used for a very long time and is mixed with different artificial hormones equivalent to estrogen and progestin.

Subsequently, whereas utilizing this medication, your physician could ask you to endure periodic well being checks. That is finished to assist medical doctors see the effectiveness of the therapy you’re taking.

As well as, be sure you comply with all physician's recommendation and / or therapist's directions. Your physician may have to alter your treatment dose or monitor you rigorously to forestall sure unwanted effects.

Don’t hesitate to see a health care provider instantly in case your situation doesn’t enhance or is getting worse. The earlier it’s handled, the simpler the therapy will likely be. The bonus is that your probabilities of getting higher sooner are additionally better.

Is medroxyprogesterone secure for pregnant and lactating girls?

There isn’t any satisfactory analysis on the dangers of utilizing medroxyprogesterone medicine in pregnant or breastfeeding girls. All the time seek the advice of your physician to weigh the potential advantages and dangers earlier than utilizing this treatment.

This drug is included within the danger of being pregnant class X based on the Meals and Drug Administration (FDA) in america, or the equal of the Meals and Drug Administration (BPOM) in Indonesia.

The next references the being pregnant danger classes based on the FDA:

  • A = Not in danger
  • B = No danger in a number of research
  • C = Possibly dangerous
  • D = There’s optimistic proof of danger
  • X = Contraindicated
  • N = Unknown

Medroxyprogesterone can enter by means of breast milk and will have an effect on the well being situation of your child. Subsequently, to keep away from numerous damaging potentialities, don’t take this medication carelessly or with out the physician's permission. Particularly in case you are actively breastfeeding.

Medroxyprogesterone Drug Interactions

What medicines could work together with medroxyprogesterone?

Drug interactions can change the efficiency of your medicines or improve the danger of significant unwanted effects. Not all potential drug interactions are listed on this doc.

Maintain an inventory of all of the merchandise you employ (together with prescription / non-prescription medicine and natural merchandise) and seek the advice of your physician or pharmacist. Don’t begin, cease, or change the dose of any treatment with out your physician's approval.

Numerous medicine which have the potential to trigger damaging interactions with medroxyprogesterone embody:

  • acarbose
  • acetohexamide
  • acitretin
  • adalimumab
  • albiglutide
  • alefacept
  • alogliptin
  • aminoglutethimide
  • amobarbital
  • amprenavir
  • anakinra
  • apalutamide
  • aprepitant
  • armodafinil
  • atazanavir
  • atorvastatin
  • bexarotene
  • boceprevir
  • bosentan
  • brigatinib
  • brivaracetam
  • butabarbital
  • butalbital
  • canagliflozin
  • canakinumab
  • carbamazepine
  • certolizumab
  • chlorpropamide
  • cholestyramine
  • cladribine
  • clarithromycin
  • clotrimazole
  • clozapine
  • cobicistat
  • colestipol
  • conivaptan
  • cyclosporine
  • dabrafenib
  • dapagliflozin
  • darunavir
  • dasatinib
  • deferasirox
  • delavirdine
  • dexamethasone
  • diltiazem
  • divalproex sodium
  • dronedarone
  • dulaglutide
  • duvelisib
  • echinacea
  • efavirenz
  • elagolix
  • elvitegravir
  • emapalumab
  • empagliflozin
  • enasidenib
  • encorafenib
  • enzalutamide
  • ertugliflozin
  • erythromycin
  • etanercept
  • etravirine
  • etretinate
  • exenatide
  • fedratinib
  • felbamate
  • flibanserin
  • fluconazole
  • fluvoxamine
  • fosamprenavir
  • fosaprepitant
  • fosphenytoin
  • fostamatinib
  • glimepiride
  • glipizide
  • glyburide

There could also be many different medicine which have the potential to trigger damaging interactions when used along with this drug. Subsequently, be sure to all the time inform all forms of medicine which are being or will likely be recurrently consumed. This easy info may be very useful for medical doctors in making choices concerning the dosage in addition to the best selection of medicine based on your situation.

Can meals or alcohol work together with medroxyprogesterone?

Sure medicine shouldn’t be used whereas consuming or consuming sure meals as a result of they’ll trigger drug interactions.

Keep away from consuming caffeine when you are utilizing this medication.

Consuming alcohol or tobacco with sure medicine may trigger interactions to happen. Please ask the physician straight for extra info.

What well being situations could work together with medroxyprogesterone?

Every other well being situations you may have can have an effect on using this drug. All the time inform your physician in case you have different well being issues, particularly:

  • Uncommon vaginal bleeding
  • Breast most cancers
  • Cervical most cancers
  • Liver illness
  • Being pregnant and breastfeeding
  • Thyroid issues
  • Blood clotting issues
  • Epilepsy and seizures
  • Pelvic ache is extreme
  • Low calcium ranges within the blood
  • Excessive ldl cholesterol
  • Hypertension (hypertension)
  • Coronary heart illness
  • Congestive coronary heart failure
  • Current coronary heart assault
  • Kidney sickness
  • Extreme headache
  • Osteroporosis
  • Lupus
  • Stroke
  • Bronchial asthma
  • Melancholy
  • Fluid retention (edema)

The above record could solely be a number of the medical situations that may work together negatively with this drug. Subsequently, convey all of your medical historical past or considerations about sure situations to the physician. The physician can carry out a lot of assessments to make sure that the drug is working properly and is secure to make use of.

Medroxyprogesterone overdose

What ought to I do in an emergency or overdose?

In case of an emergency or overdose, contact the native emergency providers supplier (119) or instantly to the closest hospital emergency division. Carry a drugs field, container, or label with you when going to the hospital to assist the physician with any obligatory info.

When somebody has an overdose, numerous signs that will come up are:

  • Too low blood stress (hypotension) which makes the pinnacle dizzy
  • Fainting
  • Quick and irregular heartbeat
  • Slower than regular coronary heart fee

What ought to I do if I miss a dose?

In case you miss a dose, take it as quickly as you bear in mind. Whether it is close to the time of the following dose, skip the missed dose and proceed in your dosing schedule. Don’t use additional doses to make up for a missed dose.

In case you proceed to overlook doses, contemplate setting an alarm or asking a member of the family to remind you.

Please seek the advice of together with your physician to debate modifications in your dosing schedule or a brand new schedule to make up for a missed dose, in case you have missed too many doses lately.

Good day Well being Group doesn’t present medical recommendation, analysis or therapy.

Good day Well being Group and Good day Sehat don’t present medical recommendation, analysis or therapy. Please examine our editorial coverage web page for extra detailed info.

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