Mefenamic Acid – A-Z Drugs

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Mefenamic Acid What drugs is it?

What’s mefenamic acid for?

Mefenamic acid, or mefenamic acid, is a drugs for treating delicate to reasonable ache. Typically used as a drugs for toothache, complications, and relieve ache throughout menstruation.

Mefenamic acid or mefenamic acid is called nonsteroidal anti-inflammatory drug (NSAID). This drug will also be used to deal with gout assaults.

Mefenamic acid dosage and mefenamic acid unwanted effects might be defined additional beneath.

What are the principles for ingesting mefenamic acid?

Mefenamic acid is normally taken Four instances a day with a glass of mineral water (Eight ounces or 240 milliliters) or as directed by a physician. Don’t lie down for at the very least 10 minutes after consuming mefenamic acid.

If abdomen problems happen, take this drugs with meals or milk. Don’t take mefenamic acid along with antacids except directed by a physician.

Sure antacids could possibly change the quantity of mefenamic acid absorbed by the physique.

Doses are given primarily based on medical circumstances and response to therapy. To scale back the danger of abdomen bleeding and different unwanted effects, take mefenamic acid on the lowest dose for a short while.

Don’t enhance your dose, drink frequently, or take longer than really helpful. Mefenamic acid shouldn’t be taken for greater than 7 days at a time.

In case you take mefenamic acid as a primary "need" (not each day), please keep in mind that it really works nicely when taken when the primary signal of ache happens. In case you watch for the indicators to worsen, the medication won’t work correctly.

In case you use mefenamic acid for menstrual ache, take your first dose instantly after menstruation or when the ache comes. Normally, you solely must devour it for the primary 2 or Three days throughout your interval.

Inform your physician in case your ache doesn’t lower or worsen or you probably have different new signs.

Methods to retailer mefenamic acid?

This drug is greatest saved at room temperature, away from direct gentle and damp locations. Don’t retailer within the lavatory. Don't freeze it.

Different manufacturers of this drug could have completely different storage guidelines. Observe the storage directions on the product packaging or ask your pharmacist. Maintain all medicines out of the attain of kids and pets.

Don’t flush drugs in the bathroom or within the sewer except instructed. Discard this product when it has expired or whether it is now not wanted.

Seek the advice of your pharmacist or native waste disposal firm about how one can safely eliminate your product.

Mefenamic Acid Dosage

The data offered just isn’t an alternative choice to medical recommendation. ALWAYS seek the advice of your physician or pharmacist earlier than beginning therapy.

What’s the dose of mefenamic acid for adults?

The next is the dose of mefenamic acid or mefenamic acid for adults aged 18 years and over:

Mefenamic acid dosage to cope with ache

  • The primary dose is 500 mg. Then, proceed with 250 mg each 6 hours as wanted
  • This drugs shouldn’t be taken greater than 7 days.

Mefenamic acid dose for menstrual ache

  • The primary dose is 500 mg. Then, proceed with 250 mg each 6 hours as wanted
  • This drugs shouldn’t be taken greater than Three days.

What’s the dose of mefenamic acid for youngsters?

The next is the dose of mefenamic acid or mefenamic acid for youngsters:

Mefenamic acid dose for youngsters 14-18 years

  • The primary dose is 500 mg. Then, proceed with 250 mg each 6 hours as wanted
  • This drugs shouldn’t be taken greater than 7 days.

Mefenamic acid or mefenamic acid just isn’t really helpful for consumption of kids below the age of 14 years.

At what dose is mefenamic acid accessible?

Mefenamic acid or mefenamic acid is on the market in capsule kind for ingesting. The content material in 1 capsule is 250 mg.

Negative effects of Mefenamic Acid (Mefenamic Acid)

What unwanted effects could be skilled resulting from mefenamic acid?

Negative effects of mefenamic acid that aren’t severe however generally happen embody:

  • Nausea, heartburn or stomach ache, diarrhea, constipation, bloating
  • Dizziness, headache, nervousness
  • Itchy pores and skin or rashes
  • Dry mouth
  • Sweating, runny nostril
  • Blurred imaginative and prescient
  • Buzz within the ear

Cease taking mefenamic acid and search medical consideration or name your physician when you’ve severe unwanted effects:

  • Chest ache, fatigue, shortness of breath, unclear speech, issues with imaginative and prescient or stability
  • Black, bloody stools, coughing up blood or vomiting that appears like espresso grounds
  • Hardly ever urinate or under no circumstances
  • Ache, warmth, or bleeding throughout urination
  • Nausea, stomach ache, fever, lack of urge for food, darkish urine, clay-colored stools, jaundice (yellowing of the pores and skin and eyes)
  • Fever, sore throat, and complications, blisters, peeling, and purple pores and skin rashes
  • Bruising, extreme tingling, numbness, muscle weak point

Not everybody experiences the next unwanted effects. There could also be some unwanted effects not talked about above.

When you have considerations about sure unwanted effects, seek the advice of your physician or pharmacist.

Warnings and Cautions for Mefenamic Acid

What medicines may work together with mefenamic acid?

Drug interactions can change the efficiency of your medicine or enhance the danger of great unwanted effects. Not all potential drug interactions are listed on this doc.

Maintain an inventory of all of the merchandise you utilize (together with prescription / nonprescription medicines and natural merchandise) and seek the advice of your physician or pharmacist. Don’t begin, cease or change the dose of any drug with out the physician's approval.

Listed here are the medicine which have the potential to trigger interactions with mefenamic acid that you’re consuming:

1. Antihypertensive medicine

Taking antihypertensive medicine along with mefenamic acid really reduces the impact of reducing blood stress. Examples of medicine included in antihypertension embody:

  • Angiotensin Receptor Blockers, akin to valsartan, candesartan, or losartan
  • angiotensin-converting enzyme (ACE) inhibitors, akin to captopril, lisinopril, enalapril
  • beta-blocker, akin to metoprolol, atenolol, thymolol

2. Diuretic medicine

The success of diuretic medicine will also be decreased if taken along with mefenamic acid. Some examples of diuretic medicine are:

  • chlorthalidone
  • torsemide
  • bumetanide

3 Nonsteroidal anti-inflammatory medicine (NSAID)

Though mefenamic acid belongs to the class of NSAID medicine, you shouldn’t devour mefenamic acid with different NSAIDs.

It’s because mefenamic acid mixed with NSAID medicine will increase the danger of bleeding and sores in your abdomen. The next are examples of NSAID medicine:

  • aspirin
  • ibuprofen
  • naproxen (Aleve, Naprosyn)
  • diclofenac (Voltaren)
  • etodolac (Lodine)
  • phenoprofen (Nalfon)
  • flurbiprofen (Ansaid)
  • indomethacin (Indocin)
  • ketoprofen (Orudis)
  • ketorolac (Toradol)
  • meclofenamate (Meclomen)
  • meloxicam (Mobic)
  • nabumetone (Relafen)
  • piroxicam (Feldene)

4. Blood thinning medicine (anticoagulants)

You must also keep away from taking blood-thinning medicines or anticoagulants throughout therapy with mefenamic acid.

5 Selective serotonin reuptake inhibitors (SSRI) and different antidepressants

Medication that have an effect on serotonin within the physique, or SSRIs, additionally trigger interactions with mefenamic acid as a result of it has the potential to trigger severe abdomen bleeding. The next are SSRI medicine that ought to be prevented:

  • citalopram (Celexa)
  • fluoxetine (Prozac, Sarafem, Symbyax)
  • sertraline (Zoloft)
  • duloxetine (Cymbalta)
  • escitalopram (Lexapro)
  • fluvoxamine (Luvox)
  • paroxetine (Paxil)
  • venlafaxine (Effexor)

Taking considered one of these medicine along with mefenamic acid may cause bruising or straightforward bleeding.

6. Different medicines

Different medicine can even enhance the danger of drug interactions if taken along with mefenamic acid:

  • cyclosporine (Gengraf, Neoral, Sandimmune)
  • lithium (Eskalith, Lithobid)
  • methotrexate (Rheumatrex, Trexall)
  • steroid (prednisone)
  • lovastatin (Mevacor)
  • ritonavir (Norvir)
  • sulfamethoxazole
  • sulfinpyrazone (Anturane)
  • trimethoprim (Proloprim)
  • zafirlukast (Accolate)

Can meals or alcohol work together with mefenamic acid?

Sure medicines shouldn’t be used when consuming or when consuming sure meals as a result of drug interactions can happen. Smoking or consuming alcohol with sure medicine can even trigger interactions to happen.

Focus on your use of medicine with meals, alcohol, or tobacco along with your well being care supplier.

What well being circumstances can work together with mefenamic acid?

Different well being issues in your physique can have an effect on the usage of this drug. Inform your physician you probably have different well being issues, akin to:

1. Bronchial asthma

Roughly 10% of bronchial asthma sufferers could have circumstances delicate to NSAID medicine, together with mefenamic acid. Bronchial asthma sufferers who devour mefenamic acid have the potential to expertise some unwanted effects akin to bronchospasm (seizures) and extreme anaphylactic reactions.

Due to this fact, in the event you undergo from bronchial asthma, inform your physician so that you just get a prescription for different medicine which can be extra applicable.

2. Edema (fluid retention or swelling within the physique)

In some instances, mefenamic acid has the potential to trigger interactions in sufferers who’ve fluid retention or edema. Some illnesses associated to this situation are hypertension and coronary heart failure.

Due to this fact, edema victims who take NSAID medicine, together with mefenamic acid, ought to get tighter supervision throughout the therapy interval.

3. Digestive issues

Individuals with digestive issues, akin to peptic ulcers or irritation of the gut, mustn’t take NSAIDs, together with mefenamic acid.

It’s because this drug has the potential to exacerbate current digestive issues, even growing the danger of bleeding within the digestive tract.

4. Kidney illness

Kidney sufferers are additionally not really helpful to devour mefenamic acid. This drug has the potential to extend creatinine ranges. Extreme creatinine ranges can set off kidney failure.

5. Liver illness

Mefenamic acid is a drug that has the potential to set off hepatotoxicity, a situation in which there’s an issue or harm to the liver.

Due to this fact, this drug shouldn’t be taken by sufferers who’ve liver issues or illnesses.

6. Hypertension

Individuals with hypertension or hypertension must also keep away from mefenamic acid medicine. This drug is vulnerable to worsening pre-existing hypertension circumstances.

7. Coronary heart and blood vessel illness

Mefenamic acid medicine must also be prevented by sufferers affected by coronary heart and blood vessel issues, akin to ischemic coronary heart illness, myocardial infarction, stroke, congestive coronary heart failure, or different vascular illnesses.

8. Anemia

Anemia victims should not suggested to devour mefenamic acid to keep away from the danger of extreme bleeding within the physique.

Drug Interactions of Mefenamic Acid (Mefenamic Acid)

What ought to be identified earlier than utilizing mefenamic acid?

Earlier than taking mefenamic acid, ensure you inform your physician about what medicines you’re taking. That is necessary to forestall interactions, drug poisoning, and harmful unwanted effects.

Along with medicine, additionally inform your physician or medical employees about any sickness or well being situation that you’re affected by. Mefenamic acid has the potential to set off interactions with sure well being circumstances.

Inform your physician if you’re pregnant, particularly if you’re within the final month of being pregnant, you intend to grow to be pregnant, or breastfeed. In case you grow to be pregnant whereas utilizing mefenamic acid, name your physician instantly.

If you will have surgical procedure, together with dental surgical procedure, inform your physician or dentist that you’re on mefenamic acid

Is mefenamic acid protected for pregnant and lactating girls?

There isn’t a satisfactory analysis on the danger of utilizing mefenamic acid in pregnant or nursing girls.

At all times seek the advice of your physician to contemplate the potential advantages and dangers earlier than utilizing this drugs.

These medicine fall into the class C danger (could also be dangerous) being pregnant in accordance with US Meals and Medication Administration (FDA)

The next are references to being pregnant danger classes in accordance with the FDA:

  • A = No danger
  • B = No danger in a number of research
  • C = Perhaps dangerous
  • D = There may be optimistic proof of danger
  • X = Contraindications
  • N = Unknown

It’s not identified whether or not mefenamant acid could be absorbed into breast milk or whether or not it’s dangerous to the infant. Don’t use this drugs with out telling your physician if you’re breastfeeding.

Mefenamic Acid Overdose

What ought to I do in an emergency or overdose?

In instances of emergency or overdose, contact the emergency providers supplier (112) or instantly to the closest hospital emergency division.

Indicators of mefenamic acid overdose embody:

  • Extreme drained
  • Nausea
  • Throws up
  • Abdomen ache
  • Vomiting bleeds and appears like espresso grounds
  • Stools are darkish and bloody
  • Sluggish respiratory
  • Coma (lack of consciousness over a time frame)

What ought to I do if I miss a dose?

In case you neglect one dose of this drugs, take it as quickly as potential. Nevertheless, when it’s nearing the following dose, skip the missed dose and return to the standard dosing schedule. Don’t double the dose.

Good day Well being Group doesn’t present medical recommendation, prognosis, or therapy.

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