Mefenamic Acid (Mefenamic Acid): Perform, Dosage, Aspect Results, How To Use – A-Z Medication

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Mefenamic Acid What Medication?

What’s mefenamic acid for?

Mefenamic acid, or mefenamic acid, is a medication to deal with gentle to reasonable ache. Typically used as a medication for toothaches, complications, and relieve ache throughout menstruation.

Mefenamic acid or mefenamic acid is named nonsteroidal anti-inflammatory medicine (NSAID). This drug will also be used to deal with gout assaults.

Mefenamic acid dosage and uncomfortable side effects of mefenamic acid are described additional under.

How do you are taking mefenamic acid?

Mefenamic acid is normally taken Four occasions a day with a glass of mineral water (Eight ounces or 240 milliliters) or as directed by your physician. Don't lie down for at the least 10 minutes after taking mefenamic acid.

If there’s upset abdomen, take this drugs with meals or milk. Don’t take mefenamic acid similtaneously an antacid except directed by your physician.

Sure antacids could change the quantity of mefenamic acid absorbed by the physique.

The dosage relies on the medical situation and response to therapy. To scale back the chance of abdomen bleeding and different uncomfortable side effects, take mefenamic acid on the lowest dose for a short while.

Don’t improve your dose, take it commonly, or take it for longer than beneficial. The drug mefenamic acid shouldn’t be taken for greater than 7 days at a time.

In case you are taking mefenamic acid as a fundamental (not each day) "need", needless to say this medicine works greatest when taken when the primary indicators of ache happen. Should you watch for the indicators to worsen, the medication received't work very nicely.

In case you are utilizing mefenamic acid for menstrual ache, take your first dose instantly after the onset of menstruation or when the ache arrives. Often, you solely must eat it for the primary 2 or Three days of your interval.

Inform your physician in case your ache doesn’t enhance or will get worse or when you’ve got different new signs.

How is mefenamic acid saved?

This medicine is greatest saved at room temperature, away from direct gentle and damp locations. Don't maintain it within the toilet. Don't freeze it.

Different manufacturers of this drug could have completely different storage guidelines. Observe the storage directions on the product bundle or ask your pharmacist. Maintain all medicines away from kids and pets.

Don’t flush medicines down the bathroom or down the drain except instructed to take action. Discard this product when it has expired or when it’s now not wanted.

Seek the advice of your pharmacist or native waste disposal firm about the best way to safely get rid of your product.

Mefenamic Acid Dosage

The knowledge offered shouldn’t be an alternative to medical recommendation. ALWAYS seek the advice of your physician or pharmacist earlier than beginning therapy.

What’s the dosage for mefenamic acid for adults?

The next is the dosage for mefenamic acid or mefenamic acid for adults aged 18 years and over:

Mefenamic acid dosage for ache administration

  • The primary dose is 500 mg. Then, proceed with 250 mg each 6 hours as wanted
  • This drugs shouldn’t be taken for greater than 7 days.

Mefenamic acid dosage for menstrual ache

  • The primary dose is 500 mg. Then, proceed with 250 mg each 6 hours as wanted
  • This drugs shouldn’t be taken for greater than Three days.

What’s the dosage for mefenamic acid for kids?

Right here is the dosage for mefenamic acid or mefenamic acid for kids:

Mefenamic acid dosage for kids 14-18 years

  • The primary dose is 500 mg. Then, proceed with 250 mg each 6 hours as wanted
  • This drugs shouldn’t be taken for greater than 7 days.

Mefenamic acid or mefenamic acid shouldn’t be beneficial for kids beneath 14 years of age.

In what dosage is mefenamic acid out there?

Mefenamic acid or mefenamic acid is offered in capsule type to drink. The content material in 1 capsule is 250 mg.

Mefenamic Acid uncomfortable side effects

What uncomfortable side effects could be skilled attributable to mefenamic acid?

Unwanted side effects of mefenamic acid that aren’t severe however do happen generally embody:

  • Nausea, heartburn or abdomen ache, diarrhea, constipation, bloating
  • Dizziness, headache, nervousness
  • The pores and skin feels itchy or has a rash
  • Dry mouth
  • Sweating, runny nostril
  • Blurred imaginative and prescient
  • Ringing within the ears

Cease taking mefenamic acid and search medical consideration or contact your physician when you might have severe uncomfortable side effects:

  • Chest ache, fatigue, shortness of breath, lack of clear speech, issues with imaginative and prescient or steadiness
  • Black, bloody stool, bloody cough or vomit that appears like espresso grounds
  • Urinating not often or in no way
  • Ache, warmth, or bleeding when urinating
  • Nausea, abdomen ache, fever, lack of urge for food, darkish urine, clay-colored stools, jaundice (yellowing of the pores and skin and eyes)
  • Fever, sore throat, and headache, pores and skin blisters, peeling, and there’s a crimson rash on the pores and skin
  • Bruising, extreme tingling, numbness, muscle weak spot

Not everybody experiences the next uncomfortable side effects. There could also be some uncomfortable side effects not listed above.

In case you have considerations about sure uncomfortable side effects, seek the advice of your physician or pharmacist.

Mefenamic Acid Drug Warnings and Cautions

What medicines could work together with mefenamic acid?

Drug interactions can change the efficiency of your drugs or improve the chance of great uncomfortable side effects. Not all potential drug interactions are listed on this doc.

Maintain a listing of all of the merchandise you utilize (together with prescription / non-prescription medicine and natural merchandise) and seek the advice of your physician or pharmacist. Don’t begin, cease, or change the dose of any drugs with out your physician's approval.

The next are medicine which have the potential to trigger interactions with mefenamic acid that you’re taking:

1. Antihypertensive medicine

Taking antihypertensive medicine along with mefenamic acid really reduces the impact of reducing blood stress. Examples of medicine included in antihypertensives embody:

  • angiotensin receptor blockers, equivalent to valsartan, candesartan, or losartan
  • angiotensin-converting enzyme (ACE) inhibitor, equivalent to captopril, lisinopril, enalapril
  • beta-blockers, equivalent to metoprolol, atenolol, timolol

2. Diuretic medicine

The efficacy of diuretic medicine will also be diminished when taken along with mefenamic acid. Some examples of diuretic medicine are:

  • chlorthalidone
  • torsemide
  • bumetanide

3. Nonsteroidal anti-inflammatory medicine (NSAID)

Though mefenamic acid is included within the class of NSAID medicine, you shouldn’t take mefenamic acid with different NSAIDs.

It is because mefenamic acid mixed with NSAIDs will increase the chance of bleeding and ulcers in your abdomen. The next are examples of NSAID medicine:

  • aspirin
  • ibuprofen
  • naproxen (Aleve, Naprosyn)
  • diclofenac (Voltaren)
  • etodolac (Lodine)
  • phenoprofen (Nalfon)
  • flurbiprofen (Ansaid)
  • indomethacin (Indocin)
  • ketoprofen (Orudis)
  • ketorolac (Toradol)
  • meclofenamate (Meclomen)
  • meloxicam (Mobic)
  • nabumetone (Relafen)
  • piroxicam (Feldene)

4.Blood thinners (anticoagulants)

You must also keep away from taking blood thinners or anticoagulants whereas taking mefenamic acid.

5. Selective serotonin reuptake inhibitor (SSRI) and different antidepressants

Medicines that have an effect on serotonin within the physique, or SSRIs, additionally work together with mefenamic acid due to the potential to trigger severe abdomen bleeding. The next are SSRI medicine that must be prevented:

  • citalopram (Celexa)
  • fluoxetine (Prozac, Sarafem, Symbyax)
  • sertraline (Zoloft)
  • duloxetine (Cymbalta)
  • escitalopram (Lexapro)
  • fluvoxamine (Luvox)
  • paroxetine (Paxil)
  • venlafaxine (Effexor)

Taking both of those medicines with mefenamic acid may cause bruising or bleed simply.

6. Different medicines

Different medicine may also improve the chance of drug interactions when taken with mefenamic acid:

  • cyclosporine (Gengraf, Neoral, Sandimmune)
  • lithium (Eskalith, Lithobid)
  • methotrexate (Rheumatrex, Trexall)
  • steroid (prednisone)
  • lovastatin (Mevacor)
  • ritonavir (Norvir)
  • sulfamethoxazole
  • sulfinpyrazone (Anturane)
  • trimethoprim (Proloprim)
  • zafirlukast (Accolate)

Can meals or alcohol work together with mefenamic acid?

Sure medicine shouldn’t be used with meals or when consuming sure meals as a result of drug interactions can happen. Smoking or consuming alcohol with sure medicine may also trigger interactions to happen.

Talk about your use of medicine with meals, alcohol, or tobacco together with your well being care supplier.

What well being circumstances could work together with mefenamic acid?

The presence of different well being issues in your physique could have an effect on the usage of this drug. Inform your physician when you’ve got different well being issues, equivalent to:

1. Bronchial asthma

About 10% of bronchial asthma sufferers could have a situation delicate to NSAID medicine, together with mefenamic acid. Bronchial asthma sufferers who take mefenamic acid have the potential to expertise a number of uncomfortable side effects equivalent to bronchospasm (seizures) and extreme anaphylactic reactions.

Due to this fact, when you’ve got bronchial asthma, inform your physician so that you could get a prescription for an additional drug that’s extra appropriate.

2.Edema (fluid retention or swelling within the physique)

In some instances, the drug mefenamic acid has the potential to trigger interactions in sufferers who’ve fluid retention or edema. A number of the ailments related to this situation are hypertension and coronary heart failure.

Due to this fact, individuals with edema who’re taking NSAIDs, together with mefenamic acid, must be intently monitored through the therapy interval.

3. Digestive issues

Individuals with digestive issues, equivalent to abdomen ulcers or colitis, shouldn’t take NSAIDs, together with mefenamic acid.

It is because these medicine have the potential to exacerbate present digestive issues and even improve the chance of bleeding within the digestive tract.

4. Kidney illness

Sufferers with kidney illness are additionally not beneficial to take mefenamic acid. This drug has the potential to extend creatinine ranges. An extreme quantity of creatinine can result in kidney failure.

5. Liver illness

Mefenamic acid is included in medicine which have the potential to set off hepatotoxicity, a situation wherein issues or injury to the liver happens.

Due to this fact, this drug shouldn’t be consumed by sufferers who’ve liver issues or ailments.

6. Hypertension

Sufferers with hypertension or hypertension must also keep away from mefenamic acid medicine. This drug carries the chance of worsening pre-existing hypertension.

7. Coronary heart and blood vessel illness

The drug mefenamic acid must also be prevented by sufferers affected by coronary heart and blood vessel issues, equivalent to ischemic coronary heart illness, myocardial infarction, stroke, congestive coronary heart failure, or different vascular illness.

8. Anemia

Anemic victims usually are not suggested to eat mefenamic acid to keep away from the chance of extreme bleeding within the physique.

Mefenamic Acid Drug Interactions (Mefenamic Acid)

What must be recognized earlier than utilizing mefenamic acid?

Earlier than taking mefenamic acid, be sure to inform your physician what drugs you’re taking. That is vital to stop interactions, drug poisoning, and harmful uncomfortable side effects.

Along with medicines, additionally inform your physician or medical personnel concerning the illness or well being situation you’re at present affected by. Mefenamic acid has the potential to set off interactions with sure well being circumstances.

Inform your physician in case you are pregnant, particularly in case you are within the final month of being pregnant, you’re planning to turn out to be pregnant, or are breastfeeding. Should you turn out to be pregnant whereas utilizing mefenamic acid, contact your physician instantly.

In case you are having surgical procedure, together with dental surgical procedure, inform your physician or dentist that you’re taking mefenamic acid

Is mefenamic acid protected for pregnant and lactating girls?

There are not any satisfactory research relating to the dangers of utilizing mefenamic acid in pregnant or nursing girls.

At all times seek the advice of your physician to weigh the potential advantages and dangers earlier than utilizing this medicine.

This drugs falls right into a class C (potential danger) being pregnant danger in accordance with US Meals and Drug Administration (FDA)

The next references the being pregnant danger classes in accordance with the FDA:

  • A = Not in danger
  • B = No danger in a number of research
  • C = Perhaps dangerous
  • D = There’s constructive proof of danger
  • X = Contraindicated
  • N = Unknown

It isn’t recognized whether or not mefenamant acid will get absorbed into breast milk or whether or not it harms the infant. Don’t use this medicine with out telling your physician in case you are breastfeeding.

Mefenamic Acid overdose

What ought to I do in an emergency or overdose?

In case of an emergency or overdose, contact the emergency providers supplier (112) or instantly to the closest hospital emergency division.

Indicators of mefenamic acid overdose embody:

  • Extreme fatigue
  • Nausea
  • Throws up
  • Abdomen ache
  • The vomit was bloody and appeared like espresso grounds
  • The stool is darkish and bloody
  • Gradual respiratory
  • Coma (lack of consciousness over a time period)

What ought to I do if I miss a dose?

Should you neglect a dose of this drugs, take it as quickly as potential. Nevertheless, when it’s nearing the time of the subsequent dose, skip the missed dose and return to the standard dosing schedule. Don't double the dose.

Hey Well being Group and Hey Sehat don’t present medical recommendation, prognosis or therapy. Please test our editorial coverage web page for extra detailed data.

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