Mefenamic Acid (Mefenamic Acid): Operate, Dosage, Facet Results, How To Use – A-Z Drugs

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Mefenamic Acid What Drugs?

What’s mefenamic acid for?

Mefenamic acid, or mefenamic acid, is a medication to deal with gentle to average ache. Usually used as a medication for toothaches, complications, and relieve ache throughout menstruation.

Mefenamic acid or mefenamic acid is named nonsteroidal anti-inflammatory medication (NSAID). This drug may also be used to deal with gout assaults.

Mefenamic acid dosage and uncomfortable side effects of mefenamic acid are described additional under.

How do you are taking mefenamic acid?

Mefenamic acid is often taken Four instances a day with a glass of mineral water (Eight ounces or 240 milliliters) or as directed by a health care provider. Don’t lie down for not less than 10 minutes after taking mefenamic acid.

If there’s upset abdomen, take this treatment with meals or milk. Don’t take mefenamic acid concurrently an antacid until directed by your physician.

Sure antacids might change the quantity of mefenamic acid absorbed by the physique.

The dosage relies on the medical situation and response to remedy. To cut back the chance of abdomen bleeding and different uncomfortable side effects, take mefenamic acid on the lowest dose for a short while.

Don’t enhance your dose, take it usually, or take it for longer than really useful. The drug mefenamic acid shouldn’t be taken for greater than 7 days at a time.

In case you are taking mefenamic acid as a primary (not every day) "need", take into account that this treatment works finest when taken when the primary indicators of ache happen. When you watch for the indicators to worsen, the drugs received't work very nicely.

In case you are utilizing mefenamic acid for menstrual ache, take your first dose instantly after the onset of menstruation or when the ache arrives. Normally, you solely have to eat it for the primary 2 or Three days of your interval.

Inform your physician in case your ache doesn’t enhance or will get worse or when you’ve got different new signs.

How is mefenamic acid saved?

This treatment is finest saved at room temperature, away from direct mild and damp locations. Don't hold it within the rest room. Don't freeze it.

Different manufacturers of this drug might have completely different storage guidelines. Observe the storage directions on the product package deal or ask your pharmacist. Maintain all medicines away from youngsters and pets.

Don’t flush medicines down the bathroom or down the drain until instructed to take action. Discard this product when it has expired or when it’s not wanted.

Seek the advice of your pharmacist or native waste disposal firm about safely eliminate your product.

Mefenamic Acid Dosage

The data supplied is just not an alternative choice to medical recommendation. ALWAYS seek the advice of your physician or pharmacist earlier than beginning remedy.

What’s the dosage for mefenamic acid for adults?

The next is the dosage for mefenamic acid or mefenamic acid for adults aged 18 years and over:

Mefenamic acid dosage for ache administration

  • The primary dose is 500 mg. Then, proceed with 250 mg each 6 hours as wanted
  • This medication shouldn’t be taken for greater than 7 days.

Mefenamic acid dosage for menstrual ache

  • The primary dose is 500 mg. Then, proceed with 250 mg each 6 hours as wanted
  • This medication shouldn’t be taken for greater than Three days.

What’s the dosage for mefenamic acid for youngsters?

Right here is the dosage for mefenamic acid or mefenamic acid for youngsters:

Mefenamic acid dosage for youngsters 14-18 years

  • The primary dose is 500 mg. Then, proceed with 250 mg each 6 hours as wanted
  • This medication shouldn’t be taken for greater than 7 days.

Mefenamic acid or mefenamic acid is just not really useful for youngsters below 14 years of age.

In what dosage is mefenamic acid obtainable?

Mefenamic acid or mefenamic acid is accessible in capsule type to drink. The content material in 1 capsule is 250 mg.

Mefenamic Acid uncomfortable side effects

What uncomfortable side effects could be skilled as a result of mefenamic acid?

Unintended effects of mefenamic acid that aren’t critical however do happen generally embody:

  • Nausea, heartburn or abdomen ache, diarrhea, constipation, bloating
  • Dizziness, headache, nervousness
  • The pores and skin feels itchy or has a rash
  • Dry mouth
  • Sweating, runny nostril
  • Blurred imaginative and prescient
  • Ringing within the ears

Cease taking mefenamic acid and search medical consideration or contact your physician when you’ve gotten critical uncomfortable side effects:

  • Chest ache, fatigue, shortness of breath, lack of clear speech, issues with imaginative and prescient or stability
  • Black, bloody stool, bloody cough or vomit that appears like espresso grounds
  • Urinating sometimes or under no circumstances
  • Ache, warmth, or bleeding when urinating
  • Nausea, abdomen ache, fever, lack of urge for food, darkish urine, clay-colored stools, jaundice (yellowing of the pores and skin and eyes)
  • Fever, sore throat, and headache, pores and skin blisters, peeling, and there’s a pink rash on the pores and skin
  • Bruising, extreme tingling, numbness, muscle weak spot

Not everybody experiences the next uncomfortable side effects. There could also be some uncomfortable side effects not listed above.

In case you have issues about sure uncomfortable side effects, seek the advice of your physician or pharmacist.

Mefenamic Acid Drug Warnings and Cautions

What medicines might work together with mefenamic acid?

Drug interactions can change the efficiency of your drugs or enhance the chance of great uncomfortable side effects. Not all potential drug interactions are listed on this doc.

Maintain a listing of all of the merchandise you utilize (together with prescription / non-prescription medication and natural merchandise) and seek the advice of your physician or pharmacist. Don’t begin, cease, or change the dose of any medication with out your physician's approval.

The next are medication which have the potential to trigger interactions with mefenamic acid that you’re taking:

1. Antihypertensive medication

Taking antihypertensive medication along with mefenamic acid truly reduces the impact of decreasing blood strain. Examples of medicine included in antihypertensives embody:

  • angiotensin receptor blockers, comparable to valsartan, candesartan, or losartan
  • angiotensin-converting enzyme (ACE) inhibitor, comparable to captopril, lisinopril, enalapril
  • beta-blockers, comparable to metoprolol, atenolol, timolol

2. Diuretic medication

The success of diuretic medication may also be diminished when taken along with mefenamic acid. Some examples of diuretic medication are:

  • chlorthalidone
  • torsemide
  • bumetanide

3. Nonsteroidal anti-inflammatory medication (NSAID)

Though mefenamic acid is included within the class of NSAID medication, you shouldn’t take mefenamic acid with different NSAIDs.

It’s because mefenamic acid mixed with NSAID medication will increase the chance of bleeding and ulcers in your abdomen. The next are examples of NSAID medication:

  • aspirin
  • ibuprofen
  • naproxen (Aleve, Naprosyn)
  • diclofenac (Voltaren)
  • etodolac (Lodine)
  • phenoprofen (Nalfon)
  • flurbiprofen (Ansaid)
  • indomethacin (Indocin)
  • ketoprofen (Orudis)
  • ketorolac (Toradol)
  • meclofenamate (Meclomen)
  • meloxicam (Mobic)
  • nabumetone (Relafen)
  • piroxicam (Feldene)

4.Blood thinners (anticoagulants)

You also needs to keep away from taking blood thinners or anticoagulants whereas taking mefenamic acid.

5. Selective serotonin reuptake inhibitor (SSRI) and different antidepressants

Medicines that have an effect on serotonin within the physique, or SSRIs, additionally work together with mefenamic acid due to the potential to trigger critical abdomen bleeding. The next are SSRI medication that needs to be prevented:

  • citalopram (Celexa)
  • fluoxetine (Prozac, Sarafem, Symbyax)
  • sertraline (Zoloft)
  • duloxetine (Cymbalta)
  • escitalopram (Lexapro)
  • fluvoxamine (Luvox)
  • paroxetine (Paxil)
  • venlafaxine (Effexor)

Taking both of those medicines with mefenamic acid may cause bruising or bleed simply.

6. Different medicines

Different medication also can enhance the chance of drug interactions when taken with mefenamic acid:

  • cyclosporine (Gengraf, Neoral, Sandimmune)
  • lithium (Eskalith, Lithobid)
  • methotrexate (Rheumatrex, Trexall)
  • steroid (prednisone)
  • lovastatin (Mevacor)
  • ritonavir (Norvir)
  • sulfamethoxazole
  • sulfinpyrazone (Anturane)
  • trimethoprim (Proloprim)
  • zafirlukast (Accolate)

Can meals or alcohol work together with mefenamic acid?

Sure medication shouldn’t be used with meals or when consuming sure meals as a result of drug interactions can happen. Smoking or consuming alcohol with sure medication also can trigger interactions to happen.

Focus on your use of medicine with meals, alcohol, or tobacco together with your well being care supplier.

What well being situations might work together with mefenamic acid?

The presence of different well being issues in your physique might have an effect on the usage of this drug. Inform your physician when you’ve got different well being issues, comparable to:

1. Bronchial asthma

About 10% of bronchial asthma sufferers might have a situation delicate to NSAID medication, together with mefenamic acid. Bronchial asthma sufferers who take mefenamic acid have the potential to expertise a number of uncomfortable side effects comparable to bronchospasm (seizures) and extreme anaphylactic reactions.

Due to this fact, when you’ve got bronchial asthma, inform your physician so to get a prescription for one more drug that’s extra appropriate.

2.Edema (fluid retention or swelling within the physique)

In some instances, the drug mefenamic acid has the potential to trigger interactions in sufferers who’ve fluid retention or edema. A number of the ailments related to this situation are hypertension and coronary heart failure.

Due to this fact, folks with edema who’re taking NSAIDs, together with mefenamic acid, needs to be carefully monitored in the course of the remedy interval.

3. Digestive issues

Folks with digestive issues, comparable to gastric ulcers or colitis, shouldn’t take NSAIDs, together with mefenamic acid.

It’s because these medication have the potential to exacerbate present digestive issues and even enhance the chance of bleeding within the digestive tract.

4. Kidney illness

Sufferers with kidney illness are additionally not really useful to take mefenamic acid. This drug has the potential to extend creatinine ranges. An extreme quantity of creatinine can result in kidney failure.

5. Liver illness

Mefenamic acid is included in medication which have the potential to set off hepatotoxicity, a situation through which issues or harm to the liver happens.

Due to this fact, this drug shouldn’t be consumed by sufferers who’ve liver issues or ailments.

6. Hypertension

Sufferers with hypertension or hypertension also needs to keep away from mefenamic acid medication. This drug is vulnerable to worsening pre-existing hypertensive situations.

7. Coronary heart and blood vessel illness

The drug mefenamic acid also needs to be prevented by sufferers affected by coronary heart and blood vessel issues, comparable to ischemic coronary heart illness, myocardial infarction, stroke, congestive coronary heart failure, or different vascular illness.

8. Anemia

Anemic victims are usually not suggested to eat mefenamic acid to keep away from the chance of extreme bleeding within the physique.

Mefenamic Acid Drug Interactions (Mefenamic Acid)

What needs to be identified earlier than utilizing mefenamic acid?

Earlier than taking mefenamic acid, be sure to inform your physician about any drugs you take. That is necessary to forestall interactions, drug poisoning, and harmful uncomfortable side effects.

Along with medicines, additionally inform your physician or medical personnel concerning the illness or well being situation you might be at the moment affected by. Mefenamic acid has the potential to set off interactions with sure well being situations.

Inform your physician in case you are pregnant, particularly in case you are within the final month of being pregnant, you might be planning to turn out to be pregnant, or are breastfeeding. When you turn out to be pregnant whereas utilizing mefenamic acid, contact your physician instantly.

In case you are having surgical procedure, together with dental surgical procedure, inform your physician or dentist that you’re taking mefenamic acid

Is mefenamic acid secure for pregnant and lactating ladies?

There are not any enough research concerning the dangers of utilizing mefenamic acid in pregnant or nursing ladies.

All the time seek the advice of your physician to weigh the potential advantages and dangers earlier than utilizing this treatment.

This medication falls right into a class C (potential danger) being pregnant danger in accordance with US Meals and Drug Administration (FDA)

The next references the being pregnant danger classes in accordance with the FDA:

  • A = Not in danger
  • B = No danger in a number of research
  • C = Possibly dangerous
  • D = There may be optimistic proof of danger
  • X = Contraindicated
  • N = Unknown

It’s not identified whether or not mefenamant acid will get absorbed into breast milk or whether or not it harms the child. Don’t use this treatment with out telling your physician in case you are breastfeeding.

Mefenamic Acid overdose

What ought to I do in an emergency or overdose?

In case of an emergency or overdose, contact the emergency companies supplier (112) or instantly to the closest hospital emergency division.

Indicators of mefenamic acid overdose embody:

  • Extreme fatigue
  • Nausea
  • Throws up
  • Abdomen ache
  • The vomit was bloody and appeared like espresso grounds
  • The stool is darkish and bloody
  • Sluggish respiratory
  • Coma (lack of consciousness over a time frame)

What ought to I do if I miss a dose?

When you neglect a dose of this medication, take it as quickly as potential. Nonetheless, when it’s nearing the time of the following dose, skip the missed dose and return to the standard dosing schedule. Don't double the dose.

Hi there Well being Group and Hi there Sehat don’t present medical recommendation, analysis or remedy. Please test our editorial coverage web page for extra detailed data.

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