Categories: Medicine A-Z

What drug Donepezil? – A-Z Medicine


Generic Name:
Donepezil


Brand:
Aldomer, Aloxtra, Alzim, Aricept, Aricept Evess, Donacept, Dozil, Fordesia, Donepezil, Donepezil, Donepezil, Donepezil and Donepezil.

Use

What is the donepezil medicine for?

Donepezil is a drug whose main function is to treat symptoms of dementia in Alzheimer's patients. This tablet medicine is included in the group enzyme blockers, which is able to restore the balance of substances that are delivering signals in the brain.

Donepezil works to improve the brain functions of Alzheimer's patients, such as memory and awareness. Even so, this drug has a different effect on each person, so it could be that using this drug the condition of Alzheimer's patients does not change or worsen.

It should be emphasized that donepezil does not treat Alzheimer's disease, because this disease will continue to develop over time, even in people who use donepezil.

These drugs are included in prescription drugs, so you cannot buy them freely and can only get them at the pharmacy if accompanied by a prescription from a doctor.

How to use donepezil?

Some things you should know and do when using Donepezil are as follows.

  • Follow all instructions given by the doctor and read all instructions for using the drug listed on the medicine packaging.
  • You may use donepezil both with and without food.
  • Swallow the tablet as a whole, do not share, chew, or crush. That can increase the risk of side effects.
  • Put the medicine tablets in your mouth, let them dissolve without chewing first. Swallow the medicinal solution in your mouth, then drink one glass of water.
  • If you want to undergo a surgical procedure or dental examination, tell your doctor if you are using donepezil. You may be asked to stop using this medicine for a while.
  • Do not stop using drugs without doctor's advice.
  • Generally, this drug is taken once a day before bedtime. If you have trouble sleeping (insomnia), communicate with your doctor about changing the time to take medication in the morning.
  • You must take the medicine according to the recommended dosage, according to your medical condition and the body's response to the medicine.
  • To reduce the risk of side effects (such as nausea and diarrhea), the doctor will give a low dose at the start and gradually increase the dose after a few weeks to a month.
  • Do not increase the dose or take this medicine more often than prescribed.
  • If you do not take donepezil for 7 days or more in a row, communicate with your doctor before starting to take this drug again. You may need to start using lower dosages to reduce the risk of side effects.
  • Use this medicine regularly to get the maximum benefit. You should take this medicine at the same time every day. It may take several weeks to get the maximum benefit from this drug.
  • Let your doctor know if your condition worsens.

How to save donepezil?

Keep this medicine in its container in a tightly closed condition. This drug is best stored at room temperature, away from direct light exposure. Place this medicine away from damp places. Do not store this medicine in the bathroom or store it in the freezer.

Another brand of this drug might have different retention rules. Observe the storage instructions on the product packaging or ask your pharmacist if you are in doubt or confused. Keep all medicines out of the reach of children and pets.

Do not flush medicine in the toilet or in the sewer unless instructed. Discard this product when it has expired or if it is no longer needed. Consult your pharmacist or local waste disposal agency about how to safely dispose of your product.

Dose

What side effects might occur due to the use of donepezil?

Get emergency medical help immediately if you have signs of allergies, such as: itching, difficulty breathing, and swelling of the face, lips, tongue, or throat.

In addition, there are some side effects that may occur after using Donepezil, including:

  • weakened heartbeat
  • the head feels light and feels like it's about to pass out
  • abdominal pain, nausea, vomiting
  • convulsions
  • difficulty urinating
  • respiratory problems
  • coughing up blood, stool bleeding or dark in color

If you experience the side effects mentioned above, contact your doctor immediately and seek professional medical help.

Meanwhile, the most common side effects are as follows:

  • diarrhea, nausea and vomiting
  • loss of appetite
  • muscle aches
  • insomnia or sleep disturbance
  • easy to feel tired
  • nervous easily
  • depression
  • easy to feel confused
  • mood swings
  • hallucination
  • unreasonable dream
  • the skin feels itchy and reddish

It is important to remember that the doctor prescribes this because the doctor has examined your body and health condition and assesses that the benefits you get from using this medicine will outweigh the risk of side effects.

Not everyone experiences the side effects mentioned. There may be some side effects not listed above. If you are worried about certain side effects you feel after using this medicine, please consult a doctor or pharmacist.

Side effects

What should you know before using Donepezil?

Some things you should do and pay attention to before deciding to use Donepezil are as follows:

  • Tell your doctor or pharmacist if you are allergic to donepezil, other piperidine medications, or ingredients contained in donepezil. Consult your doctor or pharmacist if you do not know whether you are allergic to piperidine type treatment. Ask your doctor or pharmacist about the ingredients contained in this medicine.
  • Tell your doctor or pharmacist about the type of medication (prescribed or not), vitamins, supplements, and herbal medicines that you are taking or will be taking. Your doctor may need to change the dose of your medication use or monitor you carefully to avoid side effects.
  • Tell your doctor if you weigh less than 120lb (55 kg) and if you have or have experienced bleeding in the stomach or intestine, which is caused by, for example: heartburn, irregular heartbeat, slow or even too fast, convulsions, difficulty discharging urination, asthma, chronic obstructive pulmonary disease (lung disease including chronic bronchitis or emphysema), or kidney disease, liver disorders, or heart disease.
  • Tell your doctor if you are pregnant, or plan to become pregnant, or are breastfeeding. If you become pregnant while taking Donepezil, contact your doctor as soon as possible.

Is donepezil safe for pregnant and breastfeeding women?

There is no adequate research on the risks of using this drug in pregnant or nursing women. However, you should not use this medicine if you do not or do not know the benefits and risks of this drug. Only use this medicine if the benefits outweigh the risks.

If you do not know, Consult your doctor to consider the potential benefits and risks before using this medicine. This medicine is included in pregnancy risk category C according to the US Food and Drugs Administration (FDA).

The following are references to pregnancy risk categories according to the FDA:

  • A = No risk,
  • B = No risk in some studies,
  • C = Maybe risky,
  • D = There is positive evidence of risk,
  • X = Contraindications,
  • N = Unknown

Meanwhile, there are no definitive studies about the risks that occur in infants if a nursing mother takes this drug during breastfeeding. However, you still have to consider the benefits and potential risks that arise before taking this drug.

Prevention & Warnings

What medicines can interact with donepezil?

Although certain drugs may not be taken simultaneously, in some cases, two different drugs can be used together even if interactions are possible. If this happens, your doctor may change the dose of consumption, or take other precautions if necessary.

When you take this medicine, your doctor should know if you are taking any of the medicines listed below. The following is a list of drugs chosen based on the potential for interactions that often occur and does not mean that other drugs will not react with donepezil.

Using this drug with one of the following medicines is usually not recommended, but may be needed occasionally. If the two drugs are prescribed together, your doctor can change the dosage of use or adjust how often you use one or both drugs.

  • Acrivastine
  • Bupropion
  • Fluoxetine
  • Succinylcholine

Taking this drug with one of the following medicines can cause an increased risk of certain side effects, but using these two drugs may be the best treatment for you. If the two drugs are prescribed together, your doctor will change the dosage of medication use or adjust how often you use one or both drugs.

  • Oxybutynin
  • Ramelteon
  • Tolterodine

Can food or alcohol interact with donepezil?

Certain medications should not be taken at meal times or when eating certain types of food because interactions can occur. Consuming alcohol or tobacco-derived products with certain drugs can also cause interactions. Discuss with your health care professional for the use of drugs with food, alcohol, or tobacco products.

What health conditions can interact with donepezil?

Other health conditions that you have can affect the use of this drug. Make sure you tell your doctor if you have other medical problems, especially:

  • Suffer from asthma
  • Suffered from lung disease
  • Peptic ulcer
  • Convulsions
  • Urinary obstruction or difficulty urinating. Donepezil can make conditions worse
  • Heart problems. Donepezil can have undesirable effects on heart rate
  • Liver disease
  • Weight below 50 kilograms. Donepezil can cause and increase side effects if blood pressure is high.

Interaction

What medicines can interact with donepezil?

Although certain drugs may not be taken simultaneously, in some cases, two different drugs can be used together even if interactions are possible. If this happens, your doctor may change the dose of consumption, or take other precautions if necessary.

When you take this medicine, your doctor should know if you are taking any of the medicines listed below. The following is a list of drugs chosen based on the potential for interactions that often occur and does not mean that other drugs will not react with donepezil.

Using this drug with one of the following medicines is usually not recommended, but may be needed occasionally. If the two drugs are prescribed together, your doctor can change the dosage of use or adjust how often you use one or both drugs.

  • Acrivastine
  • Bupropion
  • Fluoxetine
  • Succinylcholine

Taking this drug with one of the following medicines can cause an increased risk of certain side effects, but using these two drugs may be the best treatment for you. If the two drugs are prescribed together, your doctor will change the dosage of medication use or adjust how often you use one or both drugs.

  • Oxybutynin
  • Ramelteon
  • Tolterodine

Can food or alcohol interact with donepezil?

Certain medications should not be taken at meal times or when eating certain types of food because interactions can occur. Consuming alcohol or tobacco-derived products with certain drugs can also cause interactions. Discuss with your health care professional for the use of drugs with food, alcohol, or tobacco products.

What health conditions can interact with donepezil?

Other health conditions that you have can affect the use of this drug. Make sure you tell your doctor if you have other medical problems, especially:

  • Suffer from asthma
  • Suffered from lung disease
  • Peptic ulcer
  • Convulsions
  • Urinary obstruction or difficulty urinating. Donepezil can make conditions worse
  • Heart problems. Donepezil can have undesirable effects on heart rate
  • Liver disease
  • Weight below 50 kilograms. Donepezil can cause and increase side effects if blood pressure is high.

What should I do in an emergency or overdose?

In cases of emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

Signs of an overdose may appear after overuse of donepezil, such as:

  • nausea
  • throw up
  • saliva continues to flow
  • heartbeat slows down
  • difficulty breathing
  • weakened muscles
  • passed out
  • convulsions

What should I do if I miss a dose?

If you forget one dose of this medicine, take the dose as soon as possible. But if it turns out when you want to take a missed dose, the time has shown to take the next dose, skip the forgotten dose and return to the usual dosage schedule.

Don't double the dose because a double dose won't guarantee whether you can feel the benefits of donepezil faster than not doubling it. In addition, you do not know whether doubling the dose will not increase the risk of side effects from using the drug or not.

Always consult your doctor about the dosage of drug use, because the doctor who checks your condition certainly knows more about the use of doses that are more appropriate and in accordance with your health conditions.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Overdose

What should I do in an emergency or overdose?

In cases of emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

Signs of an overdose may appear after overuse of donepezil, such as:

  • nausea
  • throw up
  • saliva continues to flow
  • heartbeat slows down
  • difficulty breathing
  • weakened muscles
  • passed out
  • convulsions

What should I do if I miss a dose?

If you forget one dose of this medicine, take the dose as soon as possible. But if it turns out when you want to take a missed dose, the time has shown to take the next dose, skip the forgotten dose and return to the usual dosage schedule.

Don't double the dose because a double dose won't guarantee whether you can feel the benefits of donepezil faster than not doubling it. In addition, you do not know whether doubling the dose will not increase the risk of side effects from using the drug or not.

Always consult your doctor about the dosage of drug use, because the doctor who checks your condition certainly knows more about the use of doses that are more appropriate and in accordance with your health conditions.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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