Categories: Medicine A-Z

What drug Sertraline? – A-Z Medicine

Generic Name:

Anexin, Deptral, Fatral, Fridep, Iglodep, Serlof, Sernade, Zerlin, Zoloft, Antipress and Nudep.


What is Sertraline for?

Sertraline is a drug with a function to treat depression, panic attacks, obsessive compulsive disorder, post-traumatic stress disorder, social anxiety disorder (social phobia), and severe forms of premenstrual dysphoric disorder.

This medicine can improve your mood, sleep, appetite, and energy levels and can help restore your interest in daily life. This drug can reduce fear, anxiety, unwanted thoughts, and a number of panic attacks. These drugs can also reduce the urge to do repetitive tasks (encouragement such as washing hands, counting, and checking) that interfere with daily life. Sertraline is known as serotonin reuptake inhibitors (SSRIs). It works by helping to restore the balance of certain natural substances (serotonin) in the brain.

Sertraline dose and sertraline side effects will be explained further below.

How to use Sertraline?

Read the medication guide and if available read the patient information leaflet provided by your pharmacist before you start using Sertraline and every time you get a refill. If you have questions, ask your doctor or pharmacist.

Take this medication as directed by your doctor, usually once a day in the morning or evening. This tablet form of the drug can be used with or without food. This form of capsule is usually used with food after breakfast or after your dinner.

If you take this medicine for premenstrual problems, your doctor may direct you to take this medicine every day every month or just 2 weeks before your period until the beginning of your period.

The dosage is based on your medical condition and response to treatment. To reduce the risk of side effects, your doctor may direct you to start using this drug at low doses and gradually increase your dose. Follow the doctor's instructions carefully. Take this medicine regularly to get its benefits. To help you remember, use it at the same time every day.

This medicine is important to continue to take as prescribed even if you feel well. Do not stop taking this medicine without consulting your doctor. Some conditions may get worse when this drug suddenly stops. Also, you may experience symptoms such as mood swings, headaches, fatigue, sleep changes, and short feelings similar to electric shock. Your dose may need to be gradually reduced to reduce side effects. Report if there are new symptoms or the symptoms are getting worse.

Tell your doctor if your condition does not improve or worsen.

Follow the rules given by your doctor or pharmacist before starting treatment. If you have questions, consult your doctor or pharmacist.

How is Sertraline stored?

This drug is best stored at room temperature, away from direct light and damp places. Do not store in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product packaging or ask your pharmacist. Keep all medicines out of the reach of children and pets.

Do not flush medicine in the toilet or in the sewer unless instructed. Discard this product when it has expired or if it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.


The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of Sertraline for adults?

Usual Adult Dosage of Sertraline for Depression:

Initial dose: 50 mg orally once a day.

Increase in the dose of 50 mg increase not more often than weekly.

Maintenance dose: Can increase once a week, for maximum use of 200 mg once a day.

Usual Adult Dose of Sertraline for Obsessive Compulsive Disorder:

Initial dose: 50 mg orally once a day.

Increase in the dose of 50 mg increase not more often than weekly.

Maintenance dose: Can increase once a week, for maximum use of 200 mg once a day.

Usual Adult Dose for Panic Disorder:

Initial dose: 25 mg orally once a day, after one week, the dose can be increased to 50 mg once a day. Increase the dose to 50 mg increase no more often than weekly.

Maintenance dose: Can increase once a week, to a maximum of 200 mg once a day.

Usual Adult Dosage of Sertraline for Post Traumatic Stress Disorder:

Initial dose: 25 mg orally once a day, after one week, the dose can be increased to 50 mg once a day. Increase the dose to 50 mg where the increase is not more often than weekly.

Maintenance dose: Can be increased once a week, for maximum use of 200 mg once a day.

Usual Adult Dose for Social Anxiety Disorder:

Initial dose: 25 mg orally once a day, after one week, the dose can be increased to 50 mg once a day. Increase the dose to 50 mg where the increase is not more often than weekly.

Maintenance dose: Can be increased once a week, for maximum use of 200 mg once a day.

Usual Adult Dose for Premenstrual dysphoric Disorder:

Initial dose: 50 mg orally once a day, either throughout the menstrual cycle or limited to the luteal phase of the menstrual cycle (depending on clinical judgment from the doctor).

Patients who do not experience a reaction from the use of 50 mg per day dose can increase the dose (50 mg increase / menstrual cycle) to 150 mg per day when daily doses throughout the menstrual cycle, or 100 mg per day when dosing during the luteal phase of the menstrual cycle. If 100 mg per day dose is used with a luteal phase dose, a titration of 50 mg per day for three days must be utilized at the beginning of each luteal phase dose period.

What is the dose of Sertraline for children?

Safety and effectiveness have not been established in pediatric patients (less than 18 years).

In what dosages is Sertraline available?

25 mg tablet; 50 mg; 100 mg

Side effects

What side effects can be experienced due to Sertraline?

Get emergency medical help if you have signs of this allergic reaction: nausea, vomiting, sweating, itching, itching, difficulty breathing, swelling of the face, lips, tongue, or throat, or feel like you are about to faint.

Report any new symptoms or worsening symptoms to your doctor, such as: changes in mood or behavior, anxiety, panic attacks, difficulty sleeping, or if you feel impulsive, irritable, agitated, irritable, aggressive, agitated, hyperactive (mentally or physical), more depressed, or have thoughts about suicide or self-harm.

Contact your doctor if you have any of the following serious side effects:

  • Extremely rigid muscles, high fever, sweating, confusion, fast or uneven heartbeat, feeling like you're about to faint
  • Agitation, hallucinations, fever, overactive reflexes, tremors
  • Nausea, vomiting, diarrhea, loss of appetite, feeling unsteady, loss of coordination; or
  • Headaches, difficulty concentrating, memory problems, weakness, fainting, convulsions, shallow breathing or stopping breathing

Less serious side effects may include:

  • Drowsiness, dizziness, feeling tired
  • Mild nausea, stomach ache, constipation
  • Dry mouth
  • Changes in appetite or weight
  • Sleep problems (insomnia); or
  • Decreased sex drive, impotence, or difficulty experiencing orgasm

Not everyone experiences the following side effects. There may be some side effects not mentioned above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Prevention & Warnings

What do you need to know before using Sertraline?

In deciding to use a drug, the risks of taking the drug must be considered. This is the decision of you and your doctor. For this drug, the following must be considered:


Tell your doctor if you have ever had an unusual or allergic reaction to this or other medication. Also tell your health care professional if you have other types of allergies, such as for food, coloring, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Proper studies have not been conducted on the relationship of age to the effects of Sertraline in a pediatric population. Safety and efficacy have not yet been found.

Appropriate studies conducted at this time have not shown specific pediatric problems that will limit the use of Sertraline for the treatment of obsessive-compulsive disorder in children. However, safety and efficacy have not been ensured in children younger than 6 years.


The right study to date has not yet demonstrated geriatric-specific problems that would limit the use of Sertraline in older people. However, elderly patients may be more sensitive to the effects of this drug than young adults, and are more likely to have hyponatremia (low sodium in the blood), which may have to be careful and dosage adjustments are made for patients receiving Sertraline.

Is Sertraline safe for pregnant and breastfeeding women?

There is no adequate research on the risks of using this drug in pregnant or nursing women. Always consult your doctor to consider the potential benefits and risks before using this medicine. This drug is included in the risk of pregnancy category C according to the US Food and Drugs Administration (FDA).

The following are references to pregnancy risk categories according to the FDA:

  • A = No risk
  • B = No risk in several studies
  • C = Maybe risky
  • D = There is positive evidence of risk
  • X = Contraindications
  • N = Unknown

Studies in women show that this drug poses minimal risk to babies when used during breastfeeding.


What medicines might interact with Sertraline?

Drug interactions can change the performance of your medication or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / nonprescription medicines and herbal products) and consult your doctor or pharmacist. Do not start, stop or change the dose of any drug without the doctor's approval.

Although some drugs may not be taken together at all, in other cases some drugs can also be used together although interactions may occur. In cases like this, the doctor may change the dose, or do other prevention things that are needed. Let your doctor know if you are taking other medicines both over the counter and from a prescription.


Using this drug with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medicine or change some of the other medicines that you take.

  • Clorgyline
  • Furazolidone
  • Iproniazid
  • Isocarboxazid
  • Linezolid
  • Methylene Blue
  • Moclobemide
  • Nialamide
  • Pargyline
  • Phenelzine
  • Pimozide
  • Procarbazine
  • Rasagiline
  • Selegiline
  • Toloxatone
  • Tranylcypromine

Using this drug with one of the following medicines is usually not recommended, but may be needed in some cases. If the two drugs are prescribed together, your doctor can change the dosage or how often you use one or both drugs.

  • Abciximab
  • Acenocoumarol
  • Acrivastine
  • Almotriptan
  • Amitriptyline
  • Amoxapine
  • Anagrelide
  • Ancrod
  • Anisindione
  • Antithrombin III Human
  • Apixaban
  • Ardeparin
  • Aspirin
  • Astemizole
  • Bivalirudin
  • Bupropion
  • Certoparin
  • Cilostazol
  • Citalopram
  • Clomipramine
  • Clopidogrel
  • Clozapine
  • Cyclobenzaprine
  • Dalteparin
  • Danaparoid
  • Defibrotide
  • Sulfate Dermatan
  • Desipramine
  • Desirudin
  • Desvenlafaxine
  • Dexfenfluramine
  • Dextromethorphan
  • Diclofenac
  • Dicumarol
  • Dipyridamole
  • Dolasetron
  • Dothiepin
  • Doxepin
  • Duloxetine
  • Eletriptan
  • Enoxaparin
  • Eptifibatide
  • Escitalopram
  • Fenfluramine
  • Fentanyl
  • Flecainide
  • Fluoxetine
  • Fluvoxamine
  • Fondaparinux
  • Fosphenytoin
  • Frovatriptan
  • Granisetron
  • Haloperidol
  • Heparin
  • Hydroxytryptophan
  • Imipramine
  • Iobenguane I 123
  • Levomilnacipran
  • Lofepramine
  • Lorcaserin
  • Meperidine
  • Milnacipran
  • Mirtazapine
  • Nadroparin
  • Naratriptan
  • Nortriptyline
  • Oxcarbazepine
  • Oxycodone
  • Palonosetron
  • Parnaparin
  • Paroxetine
  • Pentosan Polysulfate Sodium
  • Phenindione
  • Phenprocoumon
  • Phenytoin
  • Prasugrel
  • Propafenone
  • Protriptyline
  • Reviparin
  • Risperidone
  • Ritonavir
  • Rizatriptan
  • Sibutramine
  • St. John's Wort
  • Sumatriptan
  • Tamoxifen
  • Tapentadol
  • Ticlopidine
  • Tinzaparin
  • Tirofiban
  • Tramadol
  • Trazodone
  • Trimipramine
  • Tryptophan
  • Venlafaxine
  • Vilazodone
  • Vortioxetine
  • Warfarin
  • Zolmitriptan

Using this drug with one of the following medicines can cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If the two drugs are prescribed together, your doctor can change the dosage or how often you use one or both drugs.

  • Alprazolam
  • Carbamazepine
  • Cimetidine
  • Darunavir
  • Efavirenz
  • Fluphenazine
  • Ginkgo
  • Lamotrigine
  • Lithium
  • Metoclopramide
  • Propranolol
  • Rifampin
  • Thiotepa
  • Zolpidem

Can food or alcohol interact with Sertraline?

Certain medicines should not be used when eating or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with Sertraline?

Other health problems in your body can affect the use of this drug. Tell your doctor if you have other health problems:

  • Bipolar disorder (mood disorders with mania and depression), or risk or
  • Bleeding problems or
  • Diabetes or
  • Glaucoma, closed angle, or history or
  • Hyponatremia (low sodium in the blood) or
  • Mania or hypomania, history or
  • Purpura (discoloration of purple or brownish red on the skin), a history or
  • Convulsions, history-Use with caution. Might make conditions worse
  • Liver Disease – Use with caution. The effect can be increased due to the slow cleansing of the drug from the body


What should I do in an emergency or overdose?

In cases of emergency or overdose, contact the local emergency services provider (112) or immediately to the nearest hospital emergency department.

Symptoms of an overdose may include:

  • Hair loss
  • Changes in sexual drive or ability
  • Sleepy
  • Excessive fatigue
  • Hard to sleep
  • Diarrhea
  • Throw up
  • Irregular or rapid, beating heartbeat
  • Nausea
  • Dizzy
  • Excitement
  • Shaking uncontrollably from a part of the body
  • Convulsions
  • Hallucinations (hearing voices or seeing things that don't exist)
  • Unconsciousness
  • Passed out

What should I do if I miss a dose?

If you forget one dose of this medicine, take it as soon as possible. But when it is nearing the next dose, skip the missed dose and return to the usual dosage schedule. Do not double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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