Categories: Medicine A-Z

What is Mefenamic Acid medicine for? – A-Z Medicine

Generic Name:
Mefenamic acid

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What is mefenamic acid for?

Mefenamic acid is a medicine to treat mild to moderate pain. Often used as a medicine for toothache, headaches, and relieve pain during menstruation.

Mefenamic acid or mefenamic acid is known as a nonsteroidal anti-inflammatory drug (NSAID). This drug can also be used to treat gout attacks.

Mefenamic acid dosage and mefenamic acid side effects will be explained further below.

What are the rules for drinking mefenamic acid?

Mefenamic acid is usually taken 4 times a day with a glass of mineral water (8 ounces or 240 milliliters) or as directed by a doctor. Do not lie down for at least 10 minutes after taking this medicine. If stomach disorders occur, take this medicine with food or milk. Do not take mefenamic acid together with antacids unless directed by a doctor.

Certain antacids may be able to change the amount of mefenamic acid absorbed by the body.

Doses are given based on medical conditions and response to treatment. To reduce the risk of bleeding in the stomach and other side effects, take this medicine at the lowest dose for a short time.

Do not increase your dose, drink regularly, or take longer than recommended. This drug should not be taken more than 7 days at a time.

If you are taking this drug as a basic "need" (not every day), please remember that this drug works well when taken when the first sign of pain occurs. If you wait for the signs to worsen, the medicine will not work properly.

If you use this medicine for menstrual pain, take your first dose immediately after the onset of menstruation or when the pain arrives. Usually, you only need to consume it for the first 2 or 3 days during your period.

Tell your doctor if your pain does not decrease or get worse or if you have other new symptoms.

How to store mefenamic acid?

This drug is best stored at room temperature, away from direct light and damp places. Do not store in the bathroom. Don't freeze it. Other brands of this drug may have different storage rules. Observe the storage instructions on the product packaging or ask your pharmacist. Keep all medicines out of the reach of children and pets.

Do not flush medicine in the toilet or in the sewer unless instructed. Discard this product when it has expired or if it is no longer needed. Consult your pharmacist or local waste disposal company about how to safely dispose of your product.


The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before starting treatment.

What is the dose of mefenamic acid for adults?

Mefenamic acid dose for pain relief: Mefenamic acid 500 mg followed by 250 mg every 6 hours as needed, no more than 7 days.

Mefenamic acid dose for menstrual pain: 500 mg followed by 250 mg every 6 hours since the start of menstruation.

What is the dose of mefenamic acid for children?

Mefenamic acid dose for children 14-18 years: 500 mg followed by 250 mg every 6 hours as needed, no more than 7 days.

At what dose is mefenamic acid available?

Capsules: 250 mg.

Side effects

What side effects can be experienced because of mefenamic acid?

Side effects of mefenamic acid that are not serious but sometimes occur include:

  • Nausea, heartburn or abdominal pain, diarrhea, constipation, bloating
  • Dizziness, headache, nervousness
  • Itchy skin or rashes
  • Dry mouth
  • Sweating, runny nose
  • Blurred vision
  • Buzz in the ear

Stop taking mefenamic acid and seek medical attention or call your doctor when you have serious side effects:

  • Chest pain, fatigue, shortness of breath, unclear speech, problems with vision or balance
  • Black, bloody stools, coughing up blood or vomiting that looks like coffee grounds
  • Rarely urinate or not at all
  • Pain, heat, or bleeding during urination
  • Nausea, abdominal pain, fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin and eyes)
  • Fever, sore throat, and headache, blistered skin, peeling, and red skin rashes
  • Bruising, severe tingling, numbness, muscle weakness

Not everyone experiences the following side effects. There may be some side effects not mentioned above. If you have concerns about certain side effects, consult your doctor or pharmacist.

Prevention & Warnings

What should be known before using mefenamic acid?

Before consuming mefenamic acid,

  • Tell your doctor and pharmacist if you are allergic to mefenamic acid, aspirin or other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), other medicines, other inactive ingredients in mefenamic acid capsules. Ask your pharmacist for a list of inactive ingredients
  • Tell your doctor and pharmacist what is not prescribed in the prescription medicines, vitamins, nutritional supplements, and herbal products that you consume and will consume. Be sure to mention the antacids from these drugs: antacids; angiotensin-converting enzyme (ACE) substances such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinine , ramipril (Altace), and trandolapril (Mavik); amiodarone (Cordarone, Pacerone); atazanavir (Reyataz); clopidogrel (Plavix); diuretics (‘water pills’), efavirenz (Sustiva); fluconazole (Diflucan); fluvastatin (Lescol); metronidazole (Flagyl); lithium (Eskalith, Lithobid); lovastatin (Mevacor); methotrexate (Rheumatrex); ritonavir (Norvir, in Kaletra); sulfamethoxazole (in Bactrim, Septra); sulfinpyrazone (Anturane); trimethoprim (Proloprim); and zafirlukast (Accolate). Your doctor may change the dosage of the drug or monitor you closely to see any side effects
  • Tell your doctor if you have or have experienced conditions such as: asthma, especially if you often feel nasal congestion or runny nose or nasal polyps (swelling on the inside of the nose); swelling of the hands, feet, ankles and lower legs (fluid retention); liver or kidney disease
  • Tell your doctor if you are pregnant, especially if you are in the last month of pregnancy, you plan to become pregnant, or breastfeed. If you become pregnant while using mefenamic acid, call your doctor immediately
  • If you are going for surgery, including dental surgery, tell your doctor or dentist that you are on mefenamic acid

Is mefenamic acid safe for pregnant and lactating women?

There is no adequate research on the risk of using mefenamic acid in pregnant or nursing women. Always consult your doctor to consider the potential benefits and risks before using this medicine. This drug is included in the risk of pregnancy category C (may be at risk) according to the US Food and Drugs Administration (FDA)

The following are references to pregnancy risk categories according to the FDA:

  • A = No risk
  • B = No risk in several studies
  • C = Maybe risky
  • D = There is positive evidence of risk
  • X = Contraindications
  • N = Unknown

It is not known whether mefenamant acid can be absorbed into breast milk or whether it is harmful to the baby. Do not use this medicine without telling your doctor if you are breastfeeding.


What medicines might interact with mefenamic acid?

Drug interactions can change the performance of your medication or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Keep a list of all the products you use (including prescription / nonprescription medicines and herbal products) and consult your doctor or pharmacist. Do not start, stop or change the dose of any drug without the doctor's approval.

Tell your doctor if you are taking antidepressants such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor). Taking one of these drugs together with mefenamic acid can cause bruising or easy bleeding.

Before using mefenamic acid, tell your doctor if you use any of the following drugs:

  • Blood thinners such as warfarin (Coumadin
  • Diuretic (water pill) such as furosemide (Lasix)
  • Cyclosporine (Gengraf, Neoral, Sandimmune)
  • Lithium (Eskalith, Lithobid)
  • Methotrexate (Rheumatrex, Trexall)
  • Steroids (prednisone and others); or
  • Aspirin or NSAIDs (non-steroidal anti-inflammatory drugs) such as diclofenac (Voltaren), etodolac (Lodine), phenoprofen (Nalfon), flurbiprofen (Ansaid), ibuprofen (Advil, Motrin), indomethacin (Indocin), ketoprofen (Nalfon), flurbiprofen (Ansaid), ibuprofen (Advil, Motrin), indomethacin (Indocin), ketoprofen (Nalfon), flurbiprofen (Ansaid), ibuprofen (Advil, Motrin), indomethacin (Indocin), ketoprofen (Oralfis) (Orudis) , ketorolac (Toradol), meclofenamate (Meclomen), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others

Can food or alcohol interact with mefenamic acid?

Certain medicines should not be used when eating or when eating certain foods because drug interactions can occur. Consuming alcohol or tobacco with certain drugs can also cause interactions to occur. Discuss your use of drugs with food, alcohol, or tobacco with your health care provider.

What health conditions can interact with mefenamic acid?

Other health problems in your body can affect the use of this drug. Tell your doctor if you have other health problems, specifically:

  • Anemia or
  • Asthma
  • Bleeding problem
  • Blood clots
  • Edema (fluid retention or swelling in the body)
  • History of heart attack
  • Heart disease (for example, congestive heart failure)
  • Hypertension (high blood pressure)
  • Kidney illness
  • Liver disease (for example, hepatitis)
  • Stomach or intestinal pain
  • Stroke history unakan Use with caution. This medicine can worsen the condition
  • Aspirin-sensitive asthma
  • Severe kidney disease
  • Stomach ulcers, active – this drug should not be given to patients with this condition
  • Heart surgery (for example, coronary artery bypass graft (CABG) surgery) ⎯The drug is not used to relieve pain before or after surgery


What should I do in an emergency or overdose?

In cases of emergency or overdose, contact the emergency services provider (112) or immediately to the nearest hospital emergency department.

Signs of an overdose include:

  • Excessive tired
  • Nausea
  • Throws up
  • Stomach ache
  • Vomiting bleeds and looks like coffee grounds
  • The stool is dark and bloody
  • Slow breathing
  • Coma (loss of consciousness over a period of time)

What should I do if I miss a dose?

If you forget one dose of this medicine, take it as soon as possible. However, when it is nearing the next dose, skip the missed dose and return to the usual dosage schedule. Do not double the dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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